Cheap flights from Santiago to Cusco from $164

SCL — CUZ
5 Dec — 12 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Cuzco

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Cuzco

Fri 27/1121:25 -
1 stop12h 00m
Fri 4/1212:10 -
1 stop8h 25m
Deal found 3/11$424
Mon 7/1220:35 -
1 stop11h 40m
Mon 14/1212:10 -
1 stop8h 25m
Deal found 1/11$433
Sun 20/1208:50 -
Nonstop3h 40m
Mon 21/1206:55 -
1 stop13h 40m
Deal found 3/11$444
Mon 21/1207:00 -
1 stop28h 25m
Thu 24/1212:10 -
1 stop8h 25m
Deal found 3/11$473
Sun 20/1208:50 -
Nonstop3h 40m
Mon 21/1211:30 -
Nonstop3h 14m
Deal found 3/11$474
Sun 15/1113:40 -
1 stop9h 20m
Thu 19/1112:10 -
1 stop8h 25m
Deal found 2/11$476
Thu 17/1220:35 -
1 stop19h 55m
Thu 24/1220:05 -
1 stop7h 00m
Deal found 1/11$479
Fri 4/1207:00 -
1 stop9h 30m
Fri 11/1213:20 -
1 stop7h 15m
Deal found 4/11$482
Fri 18/1208:50 -
Nonstop3h 40m
Tue 22/1222:25 -
1 stop10h 30m
Deal found 3/11$524
Mon 21/1208:50 -
Nonstop3h 40m
Thu 24/1206:55 -
1 stop13h 40m
Deal found 3/11$532
Fri 18/1208:50 -
Nonstop3h 40m
Tue 22/1211:30 -
Nonstop3h 14m
Deal found 3/11$533

Find flight deals from Santiago to Cuzco

Round-trip from

$367

One-way from

$164

Popular in

July

Cheapest in

March

Average price

$407

Good one-way deal

$358 or less
Sky Airline
  • Sky Airline
  • 8/2-14/2
  • Nonstop
  • 6h 59m total
  • Santiago to Cusco
Sky Airline
  • Sky Airline
  • 18/12-31/12
  • 1 total stop
  • 28h 25m total
  • Santiago to Cusco
Highest demand for flights based on searches. 2% potential increase in price ($12 potential increase over avg. return price).
Cheapest flight prices on average. 0% potential price decrease ($7 potential savings vs. average return price).
Average for round-trip flights in November 2026
Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete.

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Tue 23/2

06:07-15:00

1 stop10h 53m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$179

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Fri 27/11

21:25-11:30

1 stop16h 05m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$180

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Thu 19/11

07:00-21:00

1 stop16h 00m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$180

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Wed 18/11

07:00-14:25

1 stop9h 25m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$181

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 21/11

07:00-19:10

1 stop14h 10m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$217

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 25/1

21:55-09:05

1 stop13h 10m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$231

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 24/1

12:32-20:45

1 stop10h 13m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$273
Fastest return journey

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 8/2

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Sun 14/2

18:25-23:54

Nonstop3h 29m

$367

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 1/3

12:32-20:45

1 stop10h 13m

Cusco Velazco Astete

Tue 9/3

07:20-10:53

1 stop25h 33m

$377

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 1/3

12:32-20:45

1 stop10h 13m

Cusco Velazco Astete

Wed 10/3

07:55-10:53

1 stop24h 58m

$377

Flights are sorted by cheapest return flights first.

Deals found on 1/11

Showing 1-10 of 17 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

Booking 75 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Cusco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of $393). Flying from Santiago to Cusco in July is currently the most expensive (average of $476). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

It’s optimal to fly from Santiago to Cusco in the afternoon. By choosing this option you can save up to 41% on the cost of your flight, compared to a flight at midday.

How much does it cost for a return flight from Santiago to Cusco?

Airfare is typical for this route at the moment.

Santiago to Cusco flights typically cost between $349 and $479 in February.
The cheapest return price found within the last 5 days was $367 on Sky Airline (8 Feb–14 Feb).

Reviews of airlines servicing Cuzco

Read reviews from past customers who have flown with LATAM Airlines from Santiago to Cusco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.0

Boarding

7.5

Comfort

7.3

Food

6.8

Overall

7.4

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.

Crew

8.0

Boarding

7.5

Comfort

7.3

Food

6.8

Overall

7.4

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.

Related info for your journey

  • How popular is this Santiago to Cusco flight route?

  • How long is the flight from Santiago to Cusco?

    Sky Airline and JetSMART can get you from Santiago to Cusco in just under 3h 30m. Your travel time can differ by up to 6h 43m. The distance from Santiago to Cusco is about 2210 km. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Santiago to Cusco round-trip?

    Our cheapest airline available from Santiago to Cusco is LATAM Airlines. Our recent data shows that you can find tickets from as low as $338 on this airline. LATAM Airlines is 22% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Santiago to Cusco?

    Looking at all options, your cheapest flight can be booked for $358. While the most popular route (Santiago Arturo Merino Benitez - Cusco Velazco Astete) can be booked for $473 on average, our data indicates $363 when flying from Santiago to Cusco.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of $393). Flying from Santiago to Cusco in July is currently the most expensive (average of $476). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santiago to Cuzco

Top airline flying from Santiago to Cuzco

AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$338Average$643FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights

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