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Cheap flights from Santiago to Cusco from $163

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/4. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — CUZ
10 Apr — 17 Apr1
1 adult
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Cusco Velazco Astete are usually found in November or August, booked 80 days in advance, depart on a Tuesday or Monday and return on a Monday

Cheap flight deals from Santiago to Cuzco

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Cuzco
Explore the most affordable flight options available from Santiago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 March 2026.

Tue 28/404:41
SCL
-
CUZ
1 stop8h 19m
JetSMART
Fri 1/517:15
CUZ
-
SCL
1 stop9h 56m
JetSMART
Deal found 6/3$298
Sun 10/504:56
SCL
-
CUZ
1 stop11h 59m
JetSMART
Sat 16/517:20
CUZ
-
SCL
1 stop9h 51m
JetSMART
Deal found 6/3$312
Fri 17/415:16
SCL
-
CUZ
1 stop7h 34m
JetSMART
Sun 19/416:35
CUZ
-
SCL
1 stop10h 36m
JetSMART
Deal found 7/3$321
Wed 3/604:41
SCL
-
CUZ
1 stop6h 44m
JetSMART
Fri 12/606:50
CUZ
-
SCL
1 stop9h 21m
JetSMART
Deal found 9/3$326
Sun 7/604:56
SCL
-
CUZ
1 stop12h 04m
JetSMART
Sun 14/622:05
CUZ
-
SCL
1 stop28h 51m
JetSMART
Deal found 9/3$328
Wed 22/420:31
SCL
-
CUZ
1 stop23h 59m
JetSMART
Wed 29/407:00
CUZ
-
SCL
1 stop20h 16m
JetSMART
Deal found 8/3$329
Wed 22/420:31
SCL
-
CUZ
1 stop12h 34m
JetSMART
Sun 26/422:10
CUZ
-
SCL
1 stop28h 46m
JetSMART
Deal found 6/3$331
Tue 21/404:41
SCL
-
CUZ
1 stop26h 44m
JetSMART
Sun 26/422:10
CUZ
-
SCL
1 stop28h 46m
JetSMART
Deal found 6/3$332
Mon 1/604:56
SCL
-
CUZ
1 stop16h 04m
JetSMART
Sun 7/622:05
CUZ
-
SCL
1 stop28h 51m
JetSMART
Deal found 6/3$338
Wed 13/504:41
SCL
-
CUZ
1 stop17h 35m
JetSMART
Tue 19/507:55
CUZ
-
SCL
1 stop19h 01m
JetSMART
Deal found 6/3$339
Mon 8/604:56
SCL
-
CUZ
1 stop17h 09m
JetSMART
Wed 17/607:00
CUZ
-
SCL
1 stop20h 16m
JetSMART
Deal found 9/3$346

Find flight deals from Santiago to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 11 March 2026.

Round-trip from

$298

One-way from

$163

Popular in

June

Cheapest in

November

Average price

$377

Good round-trip deal

$461 or less

Good one-way deal

$211 or less
JetSMART
  • JetSMART
  • 28/4-1/5
  • 2 total stops
  • 18h 15m total
  • Santiago to Cusco
Search Deals
JetSMART
  • JetSMART
  • 18/4
  • 1 total stop
  • 8h 19m total
  • Santiago to Cusco
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($16 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete.
Search Deals
Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete.
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santiago to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 647,157 searches. Data last updated 11 March 2026.
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 21/4

04:41-06:25

1 stop26h 44m

Cusco Velazco Astete

Sun 26/4

22:10-03:56

1 stop28h 46m

$332
Fastest return journey

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 22/4

04:41-12:10

1 stop8h 29m

Cusco Velazco Astete

Mon 27/4

16:20-03:56

1 stop10h 36m

$332

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 1/6

04:56-20:00

1 stop16h 04m

Cusco Velazco Astete

Sun 7/6

22:05-03:56

1 stop28h 51m

$338

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 30/5

11:35-19:50

1 stop9h 15m

Cusco Velazco Astete

Sat 13/6

21:40-11:05

2 stops12h 25m

$364

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 20/4

00:55-17:00

2 stops17h 05m

Cusco Velazco Astete

Sun 26/4

21:40-13:30

1 stop14h 50m

$370

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 15/4

05:00-16:00

1 stop12h 00m

Cusco Velazco Astete

Sat 18/4

06:50-21:05

1 stop13h 15m

$391

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 1/6

05:00-21:00

1 stop17h 00m

Cusco Velazco Astete

Tue 30/6

21:45-13:35

1 stop14h 50m

$391

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 23/4

00:40-17:25

2 stops17h 45m

Cusco Velazco Astete

Fri 1/5

21:40-11:05

2 stops12h 25m

$394

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 30/5

00:40-17:15

2 stops17h 35m

Cusco Velazco Astete

Sun 7/6

06:50-21:05

1 stop13h 15m

$394

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 5/5

20:20-08:35

1 stop13h 15m

Cusco Velazco Astete

Wed 13/5

21:40-11:05

2 stops12h 25m

$394

Flights are sorted by cheapest return flights first.

Deals found on 6/3

Showing 1-10 of 17 resultsSorted by cheapest first
1
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Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

Use this chart to determine the optimal time to book a return flight from Santiago to Cuzco. Price data was last updated on 6 March 2026.

Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Cusco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, December is the cheapest month in which you can book a flight from Santiago to Cusco (average of $215). Flying from Santiago to Cusco in July is currently the most expensive (average of $317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

Find hourly flight availability from Santiago to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 11 March 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to Cusco as you normally would.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated 11 March 2026.
Read reviews from past customers who have flown with LATAM Airlines from Santiago to Cusco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,918 reviews
Check prices

Entertainment

7.0

Crew

8.0

Boarding

7.5

Food

6.7

Overall

7.4

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
LATAM Airlines
7.4
Good
1,918 reviews
LATAM Airlines
7.4
Good
1,918 reviews
Check prices

Entertainment

7.0

Crew

8.0

Boarding

7.5

Food

6.7

Overall

7.4

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken

Related info for your journey

Find useful and relevant information for your journey from Santiago to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Santiago to Cusco?

    Cusco Velazco Astete is the airport most travellers will use when flying to Cusco from Santiago Arturo Merino Benitez. Booking flights from Arturo Merino Benitez (SCL) to Velazco Astete (CUZ) should be relatively easy as there is 1 daily flight to Cusco from 1 airline. 7h 34m is how long a flight from Santiago to Cusco Velazco Astete will take if you book a nonstop flight.

  • How popular is this Santiago to Cusco flight route?

    This flight path from Santiago Arturo Merino Benitez to Cusco Velazco Astete was viewed by 13 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Cusco?

    JetSMART and Sky Airline can get you from Santiago to Cusco in just under 11h 59m. Your travel time can differ by up to 26m. The distance from Santiago to Cusco is about 2210 km. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Santiago to Cusco round-trip?

    Our cheapest airline available from Santiago to Cusco is LATAM Airlines. Our recent data shows that you can find tickets from as low as $333 on this airline. LATAM Airlines is 14% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Santiago to Cusco?

    Looking at all options, your cheapest flight can be booked for $200. While the most popular route (Santiago Arturo Merino Benitez - Cusco Velazco Astete) can be booked for $281 on average, our data indicates $346 when flying from Santiago to Cusco.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, December is the cheapest month in which you can book a flight from Santiago to Cusco (average of $215). Flying from Santiago to Cusco in July is currently the most expensive (average of $317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santiago to Cuzco

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to Lima flights

Top airline flying from Santiago to Cuzco

Discover the top airline that operate flights from Santiago to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 647,157 searches. Data last updated 11 March 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$333Average$461FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Santiago to Cuzco?

Deals for Santiago to Cuzco flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Santiago to Cuzco?

Cheapflights helps you find that perfect flight to Cuzco from Santiago by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Santiago to Cuzco with no change fees?

Yes! Cheapflights helps users easily find flights from Santiago to Cuzco with no change fees.

Can Cheapflights notify me if prices for flights from Santiago to Cuzco become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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