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Cheap flights from Santiago to Cusco from $148

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/3. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — CUZ
14 Nov — 21 Nov1
1 adult
1 adult, Economy

Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Cusco Velazco Astete are usually found in March or November, booked 81 days in advance, depart on a Monday or Tuesday and return on a Monday

Find flight deals from Santiago to Cuzco

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Cuzco
Explore the most affordable flight options available from Santiago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 October 2025.

Tue 11/1118:30SCL - CUZ
1 stop8h 15mLATAM Airlines
Thu 27/1105:05CUZ - SCL
1 stop8h 25mLATAM Airlines
Deal found 13/10$398
Wed 12/1121:05SCL - CUZ
1 stop11h 05mSky Airline
Wed 19/1112:10CUZ - SCL
1 stop8h 05mSky Airline
Deal found 13/10$404
Fri 7/1121:05SCL - CUZ
1 stop11h 25mSky Airline
Wed 12/1120:30CUZ - SCL
2 stops13h 45mSky Airline
Deal found 14/10$406
Thu 20/1105:59SCL - CUZ
1 stop16h 22mJetSMART
Wed 3/1212:52CUZ - SCL
1 stop14h 22mJetSMART
Deal found 13/10$409
Mon 10/1101:30SCL - CUZ
2 stops16h 31mMultiple Airlines
Thu 27/1123:10CUZ - SCL
1 stop13h 30mMultiple Airlines
Deal found 13/10$410
Wed 3/1201:30SCL - CUZ
2 stops20h 15mSky Airline
Mon 8/1212:10CUZ - SCL
2 stops22h 05mSky Airline
Deal found 14/10$417
Thu 6/1101:35SCL - CUZ
2 stops20h 10mSky Airline
Thu 13/1116:40CUZ - SCL
1 stop11h 10mSky Airline
Deal found 13/10$423
Sat 1/1105:50SCL - CUZ
1 stop14h 00mSky Airline
Tue 11/1107:05CUZ - SCL
1 stop13h 10mSky Airline
Deal found 14/10$424

Cheap flight deals from Santiago to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 15 October 2025.

Round-trip from

$339

One-way from

$148

Popular in

January

Cheapest in

March

Average price

$424
JetSMART
  • JetSMART
  • 9/3-18/3
  • 2 total stops
  • 17h 47m total
  • Santiago to Cusco
Search Deals
JetSMART
  • JetSMART
  • 7/3
  • 1 total stop
  • 10h 48m total
  • Santiago to Cusco
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($19 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santiago to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 647,157 searches. Data last updated 15 October 2025.
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Santiago

Fly to

Cuzco

Route

Depart

Return

Price

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 18/3

21:10-07:20

1 stop12h 10m

Cusco Velazco Astete

Wed 25/3

17:55-12:15

2 stops16h 20m

$404

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 12/3

01:35-17:55

2 stops18h 20m

Cusco Velazco Astete

Sun 22/3

11:40-22:15

1 stop8h 35m

$404

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 14/11

01:35-19:45

2 stops20h 10m

Cusco Velazco Astete

Wed 19/11

20:30-14:40

1 stop16h 10m

$404

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 7/11

05:50-16:05

1 stop12h 15m

Cusco Velazco Astete

Wed 12/11

20:30-12:15

2 stops13h 45m

$406

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 19/3

12:30-21:05

1 stop10h 35m

Cusco Velazco Astete

Sun 22/3

12:10-22:15

1 stop8h 05m

$406

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 1/11

05:50-17:50

1 stop14h 00m

Cusco Velazco Astete

Tue 11/11

07:05-22:15

1 stop13h 10m

$415

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 7/3

21:36-06:24

1 stop10h 48m

$148

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 27/3

06:01-20:09

1 stop16h 08m

$182

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 6/3

01:35-16:05

2 stops16h 30m

$191

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 6/3

04:35-11:10

1 stop8h 35m

$208

Flights are sorted by cheapest return flights first.

Deals found on 13/10

Showing 1-10 of 14 results
1
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Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

Use this chart to determine the optimal time to book a return flight from Santiago to Cuzco. Price data was last updated on 10 October 2025.

Booking 81 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Cusco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of $268). Flying from Santiago to Cusco in September is currently the most expensive (average of $349). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

Find hourly flight availability from Santiago to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 15 October 2025.

It’s optimal to fly from Santiago to Cusco in the evening. By choosing this option you can save up to 46% on the cost of your flight, compared to a flight at midday.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated 15 October 2025.
Read reviews from past customers who have flown with LATAM Airlines from Santiago to Cusco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,866 reviews
Check prices

Crew

8.0

Overall

7.5

Food

6.7

Comfort

7.3

Entertainment

7.0

Boarding

7.6

Reviews

1 / 20
8.0
Excellent

Darrel,Sept 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.
LATAM Airlines
7.5
Good
1,866 reviews
LATAM Airlines
7.5
Good
1,866 reviews
Check prices

Crew

8.0

Overall

7.5

Food

6.7

Comfort

7.3

Entertainment

7.0

Boarding

7.6

Reviews

1 / 20
8.0
Excellent

Darrel,Sept 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santiago to Cusco flight route?

    This flight path from Santiago Arturo Merino Benitez to Cusco Velazco Astete was viewed by 23 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Cusco?

    Sky Airline can get you from Santiago to Cusco in just under 18h 20m. Your travel time can differ by up to . The distance from Santiago to Cusco is about 2210 km.

  • What is the cheapest airline to fly from Santiago to Cusco round-trip?

    Our cheapest airline available from Santiago to Cusco is LATAM Airlines. Our recent data shows that you can find tickets from as low as $394 on this airline. LATAM Airlines is 8% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santiago to Cusco one-way?

    To fly one-way, consider booking your trip with JetSMART, which is currently one of the cheapest options available, starting at $148. Sky Airline flights start at $191 while deals on LATAM Airlines start at $208 one-way.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of $268). Flying from Santiago to Cusco in September is currently the most expensive (average of $349). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santiago to Cuzco

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to Lima flights

Top airline flying from Santiago to Cuzco

Discover the top airline that operate flights from Santiago to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 647,157 searches. Data last updated 15 October 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$394Average$459FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Santiago to Cuzco?

Deals for Santiago to Cuzco flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Santiago to Cuzco?

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