This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/3. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — CUZ
21 Feb — 28 Feb1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Cusco Velazco Astete are usually found in November or August, booked 80 days in advance, depart on a Monday or Tuesday and return on a Monday
Cheap flight deals from Santiago to Cuzco
Enter your travel dates to find the best prices.
Cheapest flights from Santiago to Cuzco
Explore the most affordable flight options available from Santiago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 January 2026.
Sat 20/608:31
SCL
-
CUZ
1 stop7h 54m
JetSMART
Sat 27/607:55
CUZ
-
SCL
1 stop8h 16m
JetSMART
Deal found 19/1$369
Thu 26/305:59
SCL
-
CUZ
1 stop11h 47m
JetSMART
Fri 27/307:02
CUZ
-
SCL
1 stop25h 37m
JetSMART
Deal found 19/1$372
Fri 24/415:11
SCL
-
CUZ
1 stop7h 39m
JetSMART
Thu 30/417:05
CUZ
-
SCL
1 stop10h 06m
JetSMART
Deal found 21/1$373
Tue 14/404:41
SCL
-
CUZ
1 stop7h 24m
JetSMART
Mon 20/416:20
CUZ
-
SCL
1 stop10h 36m
JetSMART
Deal found 20/1$375
Tue 19/501:35
SCL
-
CUZ
1 stop12h 55m
Sky Airline
Sun 31/520:25
CUZ
-
SCL
1 stop16h 15m
Sky Airline
Deal found 19/1$388
Sun 8/301:35
SCL
-
CUZ
2 stops21h 30m
Sky Airline
Mon 16/321:45
CUZ
-
SCL
2 stops12h 15m
Sky Airline
Deal found 20/1$389
Sun 29/311:26
SCL
-
CUZ
1 stop10h 54m
JetSMART
Sat 4/419:45
CUZ
-
SCL
1 stop7h 26m
JetSMART
Deal found 19/1$392
Thu 2/406:01
SCL
-
CUZ
1 stop11h 04m
JetSMART
Mon 6/416:20
CUZ
-
SCL
1 stop10h 36m
JetSMART
Deal found 19/1$395
Mon 9/301:35
SCL
-
CUZ
2 stops21h 30m
Sky Airline
Fri 20/321:45
CUZ
-
SCL
2 stops12h 15m
Sky Airline
Deal found 19/1$397
Tue 17/301:35
SCL
-
CUZ
2 stops21h 30m
Sky Airline
Mon 23/321:45
CUZ
-
SCL
2 stops12h 15m
Sky Airline
Deal found 20/1$398
Sat 28/321:15
SCL
-
CUZ
1 stop11h 20m
Sky Airline
Thu 2/416:40
CUZ
-
SCL
2 stops17h 20m
Sky Airline
Deal found 19/1$406
Best flights from Santiago to Cuzco
Discover carefully curated flight deals from Santiago to Cuzco that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 22 January 2026.
Thu 26/305:59
SCL
-
CUZ
1 stop11h 47m
JetSMART
Fri 27/307:02
CUZ
-
SCL
1 stop25h 37m
JetSMART
Deal found 19/1$372
Sun 10/501:35
SCL
-
CUZ
1 stop16h 45m
Sky Airline
Fri 15/514:05
CUZ
-
SCL
1 stop15h 35m
Sky Airline
Deal found 19/1$388
Tue 14/404:41
SCL
-
CUZ
1 stop7h 24m
JetSMART
Mon 20/416:20
CUZ
-
SCL
1 stop10h 36m
JetSMART
Deal found 20/1$375
Wed 18/305:50
SCL
-
CUZ
1 stop17h 15m
Sky Airline
Wed 25/307:05
CUZ
-
SCL
1 stop13h 10m
Sky Airline
Deal found 19/1$388
Tue 21/404:41
SCL
-
CUZ
1 stop8h 19m
JetSMART
Tue 28/416:35
CUZ
-
SCL
1 stop10h 21m
JetSMART
Deal found 20/1$375
Mon 4/520:15
SCL
-
CUZ
1 stop12h 35m
Sky Airline
Fri 8/521:45
CUZ
-
SCL
2 stops12h 15m
Sky Airline
Deal found 19/1$388
Thu 16/704:55
SCL
-
CUZ
1 stop9h 35m
Sky Airline
Sun 19/721:45
CUZ
-
SCL
1 stop15h 00m
Sky Airline
Deal found 19/1$388
Wed 20/504:55
SCL
-
CUZ
1 stop13h 25m
Sky Airline
Sun 24/520:25
CUZ
-
SCL
1 stop16h 15m
Sky Airline
Deal found 19/1$388
Fri 29/500:55
SCL
-
CUZ
2 stops17h 25m
Sky Airline
Sat 13/621:45
CUZ
-
SCL
2 stops12h 15m
Sky Airline
Deal found 19/1$388
Tue 7/401:35
SCL
-
CUZ
1 stop16h 45m
Sky Airline
Wed 15/412:05
CUZ
-
SCL
1 stop17h 35m
Sky Airline
Deal found 19/1$388
Direct flights from Santiago to Cuzco
Explore direct flight options from Santiago to Cuzco based on user searches, and compare prices and availability for your desired travel dates. Data last updated 22 January 2026.
Fri 26/619:45
SCL
-
CUZ
Nonstop3h 30m
LATAM Airlines
Tue 30/609:30
CUZ
-
SCL
Nonstop3h 20m
LATAM Airlines
Deal found 18/1$466
Fri 6/315:45
SCL
-
CUZ
Nonstop3h 30m
LATAM Airlines
Fri 13/309:30
CUZ
-
SCL
Nonstop3h 15m
LATAM Airlines
Deal found 19/1$582
Last-minute flights from Santiago to Cuzco
Discover last-minute flight deals from Santiago to Cuzco. Data last updated 22 January 2026 and is based on user searches.
Sun 22/201:35
SCL
-
CUZ
2 stops21h 30m
Sky Airline
Wed 4/317:55
CUZ
-
SCL
2 stops16h 05m
Sky Airline
Deal found 21/1$434
Tue 24/211:24
SCL
-
CUZ
1 stop11h 27m
JetSMART
Fri 6/321:32
CUZ
-
SCL
1 stop11h 07m
JetSMART
Deal found 20/1$518
Tue 24/221:05
SCL
-
CUZ
1 stop12h 15m
Sky Airline
Fri 6/307:05
CUZ
-
SCL
1 stop13h 10m
Sky Airline
Deal found 19/1$527
Wed 25/201:35
SCL
-
CUZ
2 stops21h 30m
Sky Airline
Sun 1/321:45
CUZ
-
SCL
1 stop14h 55m
Sky Airline
Deal found 19/1$570
Thu 26/205:50
SCL
-
CUZ
1 stop9h 35m
Sky Airline
Sun 8/316:50
CUZ
-
SCL
2 stops17h 10m
Sky Airline
Deal found 20/1$412
Thu 26/221:05
SCL
-
CUZ
1 stop11h 20m
Sky Airline
Mon 2/321:45
CUZ
-
SCL
1 stop14h 55m
Sky Airline
Deal found 19/1$536
Thu 26/211:24
SCL
-
CUZ
1 stop21h 02m
JetSMART
Sun 1/321:07
CUZ
-
SCL
1 stop11h 32m
JetSMART
Deal found 20/1$552
One-way flights from Santiago to Cuzco
Search for one-way flight options from Santiago to Cuzco. Find affordable one-way fares based on user searches. Data last updated 22 January 2026.
Wed 4/301:35
SCL
-
CUZ
2 stops21h 30m
Sky Airline
Deal found 19/1$185
Wed 25/301:35
SCL
-
CUZ
2 stops30h 50m
Sky Airline
Deal found 19/1$187
Thu 26/301:35
SCL
-
CUZ
2 stops18h 20m
Sky Airline
Deal found 21/1$207
Fri 20/201:35
SCL
-
CUZ
2 stops21h 40m
Sky Airline
Deal found 21/1$230
Fri 27/315:45
SCL
-
CUZ
Nonstop3h 30m
LATAM Airlines
Deal found 19/1$275
Thu 26/315:45
SCL
-
CUZ
Nonstop3h 30m
LATAM Airlines
Deal found 19/1$277
Sat 20/621:25
SCL
-
CUZ
2 stops12h 05m
LATAM Airlines
Deal found 18/1$304
Fri 20/209:15
SCL
-
CUZ
2 stops47h 11m
JetSMART
Deal found 21/1$352
Sun 8/211:24
SCL
-
CUZ
1 stop11h 02m
JetSMART
Deal found 20/1$354
Find flight deals from Santiago to Cuzco
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 22 January 2026.
Customise your flight search to find flights from Santiago to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 647,157 searches. Data last updated 22 January 2026.
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.
Fly from
Santiago
Fly to
Cuzco
Route
Depart
Return
Price
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Thu 26/3
05:59-15:46
1 stop11h 47m
Cusco Velazco Astete
Fri 27/3
07:02-10:39
1 stop25h 37m
$372
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Tue 14/4
04:41-11:05
1 stop7h 24m
Cusco Velazco Astete
Mon 20/4
16:20-03:56
1 stop10h 36m
$375
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Tue 21/4
04:41-12:00
1 stop8h 19m
Cusco Velazco Astete
Tue 28/4
16:35-03:56
1 stop10h 21m
$375
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Sun 10/5
01:35-17:20
1 stop16h 45m
Cusco Velazco Astete
Fri 15/5
14:05-06:40
1 stop15h 35m
$388
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Wed 18/3
05:50-21:05
1 stop17h 15m
Cusco Velazco Astete
Wed 25/3
07:05-22:15
1 stop13h 10m
$388
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Mon 4/5
20:15-07:50
1 stop12h 35m
Cusco Velazco Astete
Fri 8/5
21:45-11:00
2 stops12h 15m
$388
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Thu 16/7
04:55-13:30
1 stop9h 35m
Cusco Velazco Astete
Sun 19/7
21:45-13:45
1 stop15h 00m
$388
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Wed 20/5
04:55-17:20
1 stop13h 25m
Cusco Velazco Astete
Sun 24/5
20:25-13:40
1 stop16h 15m
$388
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Fri 29/5
00:55-17:20
2 stops17h 25m
Cusco Velazco Astete
Sat 13/6
21:45-11:00
2 stops12h 15m
$388
SantiagoCusco
SCL - CUZ
SCLCUZ
Santiago Arturo Merino Benitez
Tue 7/4
01:35-17:20
1 stop16h 45m
Cusco Velazco Astete
Wed 15/4
12:05-06:40
1 stop17h 35m
$388
Flights are sorted by cheapest return flights first.
Deals found on 19/1
Showing 1-10 of 15 results
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Best time to book a flight from Santiago to Cuzco
Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Cusco
Prices
Airlines
Delays
How far ahead should I book a flight from Santiago to Cusco?
Use this chart to determine the optimal time to book a return flight from Santiago to Cuzco. Price data was last updated on 16 January 2026.
Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Cusco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Santiago to Cusco?
Currently, December is the cheapest month in which you can book a flight from Santiago to Cusco (average of $225). Flying from Santiago to Cusco in September is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SCL to CUZ?
Find hourly flight availability from Santiago to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 22 January 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to Cusco as you normally would.
How much does it cost for a return flight from Santiago to Cusco?
Weekly flight availability from Santiago to Cusco
Explore weekly flight availability from Santiago to Cuzco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 22 January 2026.
The most flights from SCL to CUZ are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How often are flights from Santiago to Cusco delayed?
About 9% of weekly flights between Santiago and Cusco have experienced delays in the past year, with the average delay time being 138 minutes.
What is the most punctual flight time for Santiago to Cusco flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Wednesday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Santiago to Cusco flights?
Over the past year, LATAM Airlines have had the lowest number of delays on this route, with just 9% of flights being delayed.
Reviews of airlines servicing Cuzco
Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated 22 January 2026.
Read reviews from past customers who have flown with LATAM Airlines
from Santiago to Cusco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
Related info for your journey
Find useful and relevant information for your journey from Santiago to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Santiago to Cusco?
Cusco Velazco Astete is the airport most travellers will use when flying to Cusco from Santiago Arturo Merino Benitez. Booking flights from Arturo Merino Benitez (SCL) to Velazco Astete (CUZ) should be relatively easy as there is 1 daily flight to Cusco from 1 airline. 3h 30m is how long a flight from Santiago to Cusco Velazco Astete will take if you book a nonstop flight.
How popular is this Santiago to Cusco flight route?
This flight path from Santiago Arturo Merino Benitez to Cusco Velazco Astete was viewed by 23 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Santiago to Cusco?
JetSMART and Sky Airline can get you from Santiago to Cusco in just under 11h 47m. Your travel time can differ by up to 4h 58m. The distance from Santiago to Cusco is about 2210 km. This flight may include one or multiple stops.
What is the cheapest airline to fly from Santiago to Cusco round-trip?
Our cheapest airline available from Santiago to Cusco is LATAM Airlines. Our recent data shows that you can find tickets from as low as $421 on this airline.
What are the cheapest flights from Santiago to Cusco?
Looking at all options, your cheapest flight can be booked for $334. While the most popular route (Santiago Arturo Merino Benitez - Cusco Velazco Astete) can be booked for $401 on average, our data indicates $343 when flying from Santiago to Cusco.
Can I find deals for business class flights from Santiago to Cuzco?
Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago to Cusco?
Currently, December is the cheapest month in which you can book a flight from Santiago to Cusco (average of $225). Flying from Santiago to Cusco in September is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Cuzco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 22 January 2026.
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on 22 January 2026.
Discover the top airline that operate flights from Santiago to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 647,157 searches. Data last updated 22 January 2026.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Santiago to Cuzco?
Deals for Santiago to Cuzco flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.
Why should you use Cheapflights to find cheap flight tickets from Santiago to Cuzco?
Cheapflights helps you find that perfect flight to Cuzco from Santiago by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!
Can Cheapflights find flights from Santiago to Cuzco with no change fees?
Yes! Cheapflights helps users easily find flights from Santiago to Cuzco with no change fees.
Can Cheapflights notify me if prices for flights from Santiago to Cuzco become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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