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Cheap flights from Santiago to Cusco from $185

SCL — CUZ
22 Oct — 29 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Cuzco

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Cuzco

Fri 16/1006:12 -
1 stop17h 28m
Thu 22/1008:35 -
1 stop18h 33m
Deal found 17/9$411
Wed 7/1006:53 -
1 stop11h 57m
Thu 15/1010:45 -
1 stop9h 51m
Deal found 18/9$414
Sat 17/1020:33 -
1 stop11h 42m
Sat 24/1011:55 -
1 stop8h 41m
Deal found 18/9$415
Sun 11/1006:53 -
1 stop16h 17m
Wed 14/1021:50 -
1 stop12h 51m
Deal found 17/9$417
Sat 24/1006:12 -
1 stop16h 48m
Fri 30/1022:20 -
1 stop28h 43m
Deal found 17/9$435
Sat 7/1106:07 -
1 stop16h 38m
Sat 14/1110:55 -
1 stop16h 08m
Deal found 18/9$436
Thu 29/1006:07 -
1 stop11h 18m
Fri 6/1112:35 -
1 stop14h 28m
Deal found 17/9$438
Fri 30/1006:07 -
1 stop17h 23m
Mon 2/1107:15 -
1 stop19h 48m
Deal found 18/9$446
Fri 6/1121:55 -
1 stop11h 30m
Fri 13/1111:30 -
Nonstop3h 15m
Deal found 21/9$459
Fri 30/1006:07 -
1 stop8h 28m
Sat 7/1117:35 -
1 stop9h 28m
Deal found 17/9$460
Fri 6/1107:00 -
1 stop9h 30m
Fri 13/1119:50 -
1 stop7h 35m
Deal found 21/9$464

Find flight deals from Santiago to Cuzco

Round-trip from

$347

One-way from

$185

Popular in

July

Cheapest in

November

Average price

$456

Good one-way deal

$230 or less
Sky Airline
  • Sky Airline
  • 6/2-11/2
  • Nonstop
  • 6h 59m total
  • Santiago to Cusco
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Sky Airline
  • Sky Airline
  • 25/1-31/12
  • Nonstop
  • 3h 30m total
  • Santiago to Cusco
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. return price).
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Cheapest flight prices on average. 0% potential price decrease ($7 potential savings vs. average return price).
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Average for round-trip flights in September 2026
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Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete.
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 25/1

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$185

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 22/11

13:33-19:10

1 stop7h 37m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$219

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 18/10

06:53-16:50

1 stop11h 57m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$260

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 5/12

20:35-11:30

1 stop16h 55m

Cusco Velazco Astete

Wed 31/12

00:00-02:00

Nonstop0h 00m

$260

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 6/2

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Thu 11/2

18:00-23:29

Nonstop3h 29m

$347

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 22/2

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Sun 28/2

18:00-23:29

Nonstop3h 29m

$347

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 8/2

15:10-16:40

Nonstop3h 30m

Cusco Velazco Astete

Sun 14/2

18:00-23:29

Nonstop3h 29m

$348

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Wed 7/10

06:53-16:50

1 stop11h 57m

Cusco Velazco Astete

Thu 15/10

10:45-22:36

1 stop9h 51m

$414

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Tue 3/11

20:35-06:15

1 stop11h 40m

Cusco Velazco Astete

Tue 10/11

12:10-05:25

1 stop15h 15m

$415

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Wed 20/1

12:32-20:45

1 stop10h 13m

Cusco Velazco Astete

Sat 23/1

21:30-10:53

1 stop11h 23m

$434

Flights are sorted by cheapest return flights first.

Deals found on 18/9

Showing 1-10 of 14 resultsSorted by cheapest first
1
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Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

Booking 75 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Cusco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, November is the cheapest month in which you can book a flight from Santiago to Cusco (average of $361). Flying from Santiago to Cusco in July is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

It’s optimal to fly from Santiago to Cusco in the evening. By choosing this option you can save up to 40% on the cost of your flight, compared to a flight at midday.

How much does it cost for a return flight from Santiago to Cusco?

Airfare is below average for this route at the moment.

Santiago to Cusco flights typically cost between $396 and $525 in January.
The cheapest return price found within the last 5 days was $347 on Sky Airline (9 Jan–14 Jan).

Reviews of airlines servicing Cuzco

Read reviews from past customers who have flown with LATAM Airlines from Santiago to Cusco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,981 reviews
Check prices

Overall

7.4

Comfort

7.3

Food

6.7

Boarding

7.5

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.
LATAM Airlines
7.4
Good
1,981 reviews
LATAM Airlines
7.4
Good
1,981 reviews
Check prices

Overall

7.4

Comfort

7.3

Food

6.7

Boarding

7.5

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.

Related info for your journey

  • What airports do I use to fly from Santiago to Cusco?

    Cusco Velazco Astete is the airport most travellers will use when flying to Cusco from Santiago Arturo Merino Benitez. Booking flights from Arturo Merino Benitez (SCL) to Velazco Astete (CUZ) should be relatively easy as there is 1 daily flight to Cusco from 1 airline. 9h 30m is how long a flight from Santiago to Cusco Velazco Astete will take if you book a nonstop flight.

  • How popular is this Santiago to Cusco flight route?

    This flight path from Santiago Arturo Merino Benitez to Cusco Velazco Astete was viewed by 19 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Cusco?

    Sky Airline can get you from Santiago to Cusco in just under 3h 30m. Your travel time will be generally consistent. The distance from Santiago to Cusco is about 2210 km. All flights are typically direct.

  • What is the cheapest airline to fly from Santiago to Cusco round-trip?

    Our cheapest airline available from Santiago to Cusco is LATAM Airlines. Our recent data shows that you can find tickets from as low as $332 on this airline. LATAM Airlines is 20% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Santiago to Cusco?

    Looking at all options, your cheapest flight can be booked for $218. While the most popular route (Santiago Arturo Merino Benitez - Cusco Velazco Astete) can be booked for $464 on average, our data indicates $242 when flying from Santiago to Cusco.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, November is the cheapest month in which you can book a flight from Santiago to Cusco (average of $361). Flying from Santiago to Cusco in July is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santiago to Cuzco

Santiago to Lima flights

Top airline flying from Santiago to Cuzco

AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$332Average$605FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights

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