$191+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MEL
21 Feb — 28 Feb1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 22 January 2026.

Good one-way deal

$608 or less
Price to beat on a one-way flight from Panama.
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Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 22 January 2026.

Sat 7/309:45
PTY
-
SAL
1 stop6h 55m
Avianca
Sat 21/308:00
SAL
-
PTY
1 stop7h 55m
Avianca
Deal found 20/1$308
Sat 14/311:25
PTY
-
SAL
1 stop10h 40m
Avianca
Sun 15/315:45
SAL
-
PTY
Nonstop2h 10m
Avianca
Deal found 21/1$314
Sat 4/405:30
PTY
-
SAL
Nonstop2h 00m
Avianca
Sat 18/407:30
SAL
-
PTY
1 stop6h 25m
Avianca
Deal found 20/1$323
Sat 14/221:01
PTY
-
SAL
Nonstop2h 09m
Copa Airlines
Wed 18/213:45
SAL
-
PTY
Nonstop2h 07m
Copa Airlines
Deal found 20/1$335
Fri 13/212:29
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Sun 22/205:03
CLO
-
PTY
Nonstop1h 31m
Copa Airlines
Deal found 21/1$358
Sun 1/219:50
PTY
-
SAL
Nonstop2h 05m
Avianca
Mon 2/207:30
SAL
-
PTY
1 stop6h 25m
Avianca
Deal found 21/1$358
Wed 1/405:30
PTY
-
SAL
Nonstop2h 00m
Avianca
Sun 19/407:30
SAL
-
PTY
Nonstop2h 00m
Avianca
Deal found 20/1$367
Wed 1/405:30
PTY
-
SAL
Nonstop2h 00m
Avianca
Sat 18/422:05
SAL
-
PTY
1 stop11h 05m
Avianca
Deal found 20/1$382
Sun 5/405:30
PTY
-
SAL
Nonstop2h 00m
Avianca
Wed 15/407:30
SAL
-
PTY
Nonstop2h 00m
Avianca
Deal found 20/1$409
Fri 13/216:00
PTY
-
CLO
Nonstop1h 50m
Copa Airlines
Thu 19/215:11
CLO
-
PTY
Nonstop1h 33m
Copa Airlines
Deal found 20/1$412
Tue 3/221:01
PTY
-
SAL
Nonstop2h 09m
Copa Airlines
Thu 5/205:02
SAL
-
PTY
Nonstop2h 09m
Copa Airlines
Deal found 21/1$421
Sun 5/405:30
PTY
-
SAL
Nonstop2h 00m
Avianca
Sat 18/409:25
SAL
-
PTY
1 stop6h 05m
Avianca
Deal found 20/1$425

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 22 January 2026. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Melbourne

Route

Depart

Return

Price

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 7/3

15:50-16:50

Nonstop2h 00m

San Salvador El Salvador Intl

Sat 21/3

07:30-10:30

Nonstop2h 00m

$308

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 8/3

15:50-16:50

Nonstop2h 00m

San Salvador El Salvador Intl

Sun 22/3

07:30-10:30

Nonstop2h 00m

$308

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 14/3

11:25-21:05

1 stop10h 40m

San Salvador El Salvador Intl

Sun 15/3

15:45-18:55

Nonstop2h 10m

$314

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 25/2

19:25-20:39

Nonstop2h 14m

San Salvador El Salvador Intl

Sat 28/2

07:30-10:36

Nonstop2h 06m

$335

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 7/2

11:33-12:43

Nonstop2h 10m

San Salvador El Salvador Intl

Thu 12/2

05:02-08:11

Nonstop2h 09m

$335

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 14/2

21:01-22:10

Nonstop2h 09m

San Salvador El Salvador Intl

Sun 22/2

13:45-16:52

Nonstop2h 07m

$335

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 14/2

21:01-22:10

Nonstop2h 09m

San Salvador El Salvador Intl

Wed 18/2

13:45-16:52

Nonstop2h 07m

$335

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 1/2

19:50-20:55

Nonstop2h 05m

San Salvador El Salvador Intl

Mon 2/2

07:30-14:55

1 stop6h 25m

$358

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 6/2

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Mon 9/2

12:03-13:35

Nonstop1h 32m

$358

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 9/4

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 14/4

05:00-06:34

Nonstop1h 34m

$358

Flights are sorted by cheapest return flights first.

Deals found on 21/1

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Managua Augusto C Sandino, with prices starting at $601. Explore other affordable destinations below.

Managua Augusto C Sandino
Managua Augusto C Sandino
From $601
Istanbul
Istanbul
From $1,118
Amsterdam Schiphol
Amsterdam Schiphol
From $1,477

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Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 22 January 2026.

  • How does Cheapflights help users find flights from Panama?

    When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

  • Can Cheapflights find flights from Panama with no change fees?

    Yes! Cheapflights helps users easily find flights from Panama with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama?

Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Panama with no change fees?

Yes! Cheapflights helps users easily find flights from Panama with no change fees.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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