$188+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MEL
23 Mar — 30 Mar1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 21 February 2026.

Good round-trip deal

$559 or less

Good one-way deal

$156 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Enter your travel dates to find the best prices.

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 21 February 2026.

Mon 4/505:30
PTY
-
SAL
Nonstop2h 00m
Avianca
Sun 24/507:30
SAL
-
PTY
Nonstop2h 00m
Avianca
Deal found 17/2$329
Tue 3/321:01
PTY
-
SAL
Nonstop2h 09m
Copa Airlines
Sat 7/313:45
SAL
-
PTY
Nonstop2h 07m
Copa Airlines
Deal found 19/2$375
Wed 3/617:55
PTY
-
CLO
1 stop5h 10m
Avianca
Wed 10/608:25
CLO
-
PTY
1 stop5h 50m
Avianca
Deal found 18/2$397
Thu 12/311:33
PTY
-
SAL
Nonstop2h 10m
Copa Airlines
Fri 13/308:35
SAL
-
PTY
Nonstop2h 06m
Copa Airlines
Deal found 21/2$402
Fri 10/409:25
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Mon 13/408:46
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 18/2$415
Wed 15/421:55
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Fri 15/512:06
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 20/2$416
Tue 21/715:55
PTY
-
CLO
Nonstop1h 40m
Copa Airlines
Mon 27/705:00
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 18/2$432
Wed 1/712:30
PTY
-
CLO
Nonstop1h 40m
Copa Airlines
Mon 6/718:16
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 20/2$448
Sun 15/316:00
PTY
-
CLO
Nonstop1h 49m
Copa Airlines
Tue 24/312:02
CLO
-
PTY
Nonstop1h 32m
Copa Airlines
Deal found 18/2$455
Thu 5/319:50
PTY
-
SAL
Nonstop2h 05m
Avianca
Fri 20/308:00
SAL
-
PTY
1 stop7h 55m
Avianca
Deal found 20/2$456
Fri 20/309:25
PTY
-
CLO
Nonstop1h 39m
Copa Airlines
Fri 27/308:48
CLO
-
PTY
Nonstop1h 32m
Copa Airlines
Deal found 20/2$470
Tue 3/309:45
PTY
-
SAL
2 stops12h 35m
Avianca
Thu 19/322:05
SAL
-
PTY
1 stop9h 45m
Avianca
Deal found 20/2$560

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 21 February 2026. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Melbourne

Route

Depart

Return

Price

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 3/5

03:05-11:05

1 stop9h 00m

San Salvador El Salvador Intl

Sun 24/5

07:30-10:30

Nonstop2h 00m

$329

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 8/3

22:28-23:37

Nonstop2h 09m

San Salvador El Salvador Intl

Tue 10/3

05:02-08:11

Nonstop2h 09m

$375

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 12/3

21:01-22:10

Nonstop2h 09m

San Salvador El Salvador Intl

Sun 15/3

13:45-16:52

Nonstop2h 07m

$375

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Tue 3/3

21:01-22:10

Nonstop2h 09m

San Salvador El Salvador Intl

Sat 7/3

13:45-16:52

Nonstop2h 07m

$375

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 3/6

17:55-23:05

1 stop5h 10m

Cali Alfonso B. Aragon Intl

Wed 10/6

12:50-17:00

1 stop4h 10m

$398

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 12/3

11:33-12:43

Nonstop2h 10m

San Salvador El Salvador Intl

Fri 13/3

08:35-11:41

Nonstop2h 06m

$402

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 7/8

19:25-20:31

Nonstop2h 06m

San Salvador El Salvador Intl

Tue 11/8

08:30-11:41

Nonstop2h 11m

$402

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 1/8

11:33-12:39

Nonstop2h 06m

San Salvador El Salvador Intl

Sun 6/9

04:54-08:05

Nonstop2h 11m

$402

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 5/3

12:29-14:09

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

Mon 9/3

05:03-06:34

Nonstop1h 31m

$415

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 9/4

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 14/4

12:06-13:40

Nonstop1h 34m

$415

Flights are sorted by cheapest return flights first.

Deals found on 18/2

Showing 1-10 of 55 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Medellín Jose Maria Cordova Intl, with prices starting at $156. Explore other affordable destinations below.

Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $156
Miami
Miami
From $362
Bogotá El Dorado
Bogotá El Dorado
From $366
Montego Bay Sangster Intl
Montego Bay Sangster Intl
From $559

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Direct flights from Central America

Book a direct flight from one of these other cities located in Central America.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 21 February 2026.

  • How does Cheapflights help users find flights from Panama?

    When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

  • Can Cheapflights find flights from Panama with no change fees?

    Yes! Cheapflights helps users easily find flights from Panama with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama?

Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Panama with no change fees?

Yes! Cheapflights helps users easily find flights from Panama with no change fees.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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