$176+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 14/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MEL
8 Apr — 15 Apr1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 9 March 2026.

Good round-trip deal

$562 or less

Good one-way deal

$99 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Enter your travel dates to find the best prices.

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 9 March 2026.

Fri 20/319:25
PTY
-
SAL
Nonstop2h 14m
Copa Airlines
Mon 23/305:02
SAL
-
PTY
Nonstop2h 09m
Copa Airlines
Deal found 4/3$332
Tue 7/415:50
PTY
-
SAL
Nonstop2h 00m
Avianca
Tue 28/422:55
SAL
-
PTY
Nonstop2h 00m
Avianca
Deal found 6/3$334
Sat 28/322:28
PTY
-
SAL
Nonstop2h 09m
Copa Airlines
Fri 3/404:57
SAL
-
PTY
Nonstop2h 08m
Copa Airlines
Deal found 6/3$361
Fri 20/311:25
PTY
-
SAL
1 stop6h 05m
Avianca
Tue 24/322:05
SAL
-
PTY
1 stop17h 50m
Avianca
Deal found 4/3$384
Wed 1/411:33
PTY
-
SAL
Nonstop2h 08m
Copa Airlines
Sun 5/404:57
SAL
-
PTY
Nonstop2h 08m
Copa Airlines
Deal found 6/3$398
Fri 20/302:55
PTY
-
SAL
1 stop9h 10m
Avianca
Wed 25/322:05
SAL
-
PTY
1 stop9h 45m
Avianca
Deal found 7/3$406
Tue 7/411:33
PTY
-
SAL
Nonstop2h 08m
Copa Airlines
Tue 14/404:57
SAL
-
PTY
Nonstop2h 08m
Copa Airlines
Deal found 8/3$407
Thu 7/510:10
PTY
-
CLO
1 stop4h 00m
Avianca
Thu 21/510:15
CLO
-
PTY
1 stop4h 00m
Avianca
Deal found 4/3$427
Fri 1/522:28
PTY
-
SAL
Nonstop2h 08m
Copa Airlines
Sun 3/504:53
SAL
-
PTY
Nonstop2h 12m
Copa Airlines
Deal found 8/3$434
Tue 21/405:30
PTY
-
SAL
Nonstop2h 00m
Avianca
Sat 2/522:05
SAL
-
PTY
1 stop10h 10m
Avianca
Deal found 8/3$435
Sat 21/317:50
PTY
-
CLO
1 stop12h 20m
Avianca
Thu 26/313:10
CLO
-
PTY
1 stop11h 50m
Avianca
Deal found 5/3$438
Tue 2/603:25
PTY
-
CLO
1 stop4h 15m
Avianca
Wed 10/604:40
CLO
-
PTY
1 stop4h 35m
Avianca
Deal found 5/3$460

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 9 March 2026. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 3/4

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Fri 10/4

08:33-11:38

Nonstop2h 05m

$332

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 5/9

19:25-20:31

Nonstop2h 06m

San Salvador El Salvador Intl

Sun 13/9

08:30-11:41

Nonstop2h 11m

$332

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 1/4

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 5/4

08:33-11:38

Nonstop2h 05m

$332

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 7/8

11:33-12:39

Nonstop2h 06m

San Salvador El Salvador Intl

Tue 11/8

04:54-08:05

Nonstop2h 11m

$332

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 15/5

19:25-20:33

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 17/5

13:58-17:10

Nonstop2h 12m

$332

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 21/3

19:25-20:39

Nonstop2h 14m

San Salvador El Salvador Intl

Mon 23/3

07:30-10:36

Nonstop2h 06m

$332

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Tue 7/4

05:30-06:30

Nonstop2h 00m

San Salvador El Salvador Intl

Tue 28/4

10:10-14:55

1 stop3h 45m

$334

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 19/4

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 26/4

04:57-08:05

Nonstop2h 08m

$361

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 2/4

19:25-20:33

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 5/4

08:33-11:38

Nonstop2h 05m

$361

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 28/3

22:28-23:37

Nonstop2h 09m

San Salvador El Salvador Intl

Fri 3/4

04:57-08:05

Nonstop2h 08m

$361

Flights are sorted by cheapest return flights first.

Deals found on 4/3

Showing 1-10 of 59 resultsSorted by cheapest first
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Cartagena Rafael Nunez, with prices starting at $99. Explore other affordable destinations below.

Cartagena Rafael Nunez
Cartagena Rafael Nunez
From $99
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $157
Miami
Miami
From $363
Bogotá El Dorado
Bogotá El Dorado
From $368

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Direct flights from Central America

Book a direct flight from one of these other cities located in Central America.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 9 March 2026.

  • How does Cheapflights help users find flights from Panama?

    When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

  • Can Cheapflights find flights from Panama with no change fees?

    Yes! Cheapflights helps users easily find flights from Panama with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama?

Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Panama with no change fees?

Yes! Cheapflights helps users easily find flights from Panama with no change fees.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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