$180+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 26/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MEL
4 Dec — 11 Dec1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 4 November 2025.

Good round-trip deal

$94 or less

Good one-way deal

$627 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Enter your travel dates to find the best prices.

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 4 November 2025.

Mon 24/1109:20PTY - CLO
Nonstop1h 41mCopa Airlines
Thu 27/1104:52CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 4/11$342
Mon 24/1102:55PTY - CLO
1 stop4h 15mAvianca
Wed 3/1208:40CLO - PTY
1 stop5h 20mAvianca
Deal found 2/11$350
Wed 17/1215:55PTY - CLO
Nonstop1h 42mCopa Airlines
Wed 21/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 3/11$400
Sat 6/1215:50PTY - SAL
Nonstop2h 00mAvianca
Mon 29/1207:30SAL - PTY
Nonstop2h 00mAvianca
Deal found 2/11$402
Tue 18/1102:55PTY - SAL
1 stop9h 10mAvianca
Thu 20/1107:30SAL - PTY
Nonstop2h 00mAvianca
Deal found 3/11$405
Sat 6/1202:55PTY - SAL
1 stop9h 10mAvianca
Tue 30/1210:10SAL - PTY
1 stop3h 45mAvianca
Deal found 3/11$414
Sat 29/1109:20PTY - CLO
Nonstop1h 41mCopa Airlines
Mon 8/1215:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 3/11$416
Fri 14/1111:33PTY - SAL
Nonstop2h 08mCopa Airlines
Sat 29/1107:30SAL - PTY
Nonstop2h 08mCopa Airlines
Deal found 3/11$434
Wed 3/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Wed 10/1215:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 3/11$446
Wed 17/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Wed 24/1206:07CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 2/11$457
Fri 14/1109:20PTY - CLO
Nonstop1h 41mCopa Airlines
Sat 15/1104:52CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 3/11$465
Fri 12/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Mon 15/1208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 3/11$474

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 4 November 2025. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Melbourne

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 24/11

09:20-11:01

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Thu 27/11

04:52-06:24

Nonstop1h 32m

$342

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 14/11

09:20-11:01

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sun 16/11

08:48-10:20

Nonstop1h 32m

$342

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 24/11

09:20-11:01

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Fri 28/11

04:52-06:24

Nonstop1h 32m

$342

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 24/11

09:20-11:01

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sun 30/11

08:48-10:20

Nonstop1h 32m

$342

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 22/11

09:20-11:01

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Mon 24/11

15:12-16:44

Nonstop1h 32m

$342

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 23/3

09:25-11:04

Nonstop1h 39m

Cali Alfonso B. Aragon Intl

Mon 23/3

15:11-16:44

Nonstop1h 33m

$342

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 20/3

16:00-17:49

Nonstop1h 49m

Cali Alfonso B. Aragon Intl

Sun 22/3

08:48-10:20

Nonstop1h 32m

$342

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 11/2

16:00-17:50

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Tue 17/2

08:48-10:20

Nonstop1h 32m

$342

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 29/11

09:20-11:01

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Mon 8/12

15:11-16:44

Nonstop1h 33m

$342

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 5/12

02:55-11:05

1 stop9h 10m

San Salvador El Salvador Intl

Mon 29/12

07:30-10:30

Nonstop2h 00m

$402

Flights are sorted by cheapest return flights first.

Deals found on 2/11

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, September is the cheapest month in which you can book a flight from Panama (average of $2,935). Flying from Panama in June will prove the most costly (average of $4,804). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Bogotá El Dorado, with prices starting at $94. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From $94
Managua Augusto C Sandino
Managua Augusto C Sandino
From $620

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Central America

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Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 4 November 2025.

  • What is the cheapest month to fly from Panama?

    Currently, the cheapest month for flights from Panama is September. The most expensive month for flights is June. The cheapest prices are shown above but prices will vary according to departure times, airlines, class and how early you book.

  • How does Cheapflights help users find flights from Panama?

    When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

  • Can Cheapflights find flights from Panama with no change fees?

    Yes! Cheapflights helps users easily find flights from Panama with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama?

Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Panama with no change fees?

Yes! Cheapflights helps users easily find flights from Panama with no change fees.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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