$207+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MEL
8 Feb — 15 Feb1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 9 January 2026.

Good one-way deal

$612 or less
Price to beat on a one-way flight from Panama.
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Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on 9 January 2026.

Fri 13/216:00PTY - CLO
Nonstop1h 50mCopa Airlines
Wed 18/208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 8/1$404
Thu 2/411:33PTY - SAL
Nonstop2h 08mCopa Airlines
Sun 5/414:02SAL - PTY
Nonstop2h 08mCopa Airlines
Deal found 7/1$424
Wed 21/117:50PTY - CLO
1 stop4h 45mAvianca
Sat 31/111:50CLO - PTY
1 stop5h 05mAvianca
Deal found 7/1$442
Fri 13/221:55PTY - CLO
Nonstop1h 41mCopa Airlines
Fri 20/208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 7/1$446
Wed 25/219:50PTY - SAL
Nonstop2h 05mAvianca
Wed 11/315:45SAL - PTY
Nonstop2h 10mAvianca
Deal found 7/1$455
Sun 15/321:55PTY - CLO
Nonstop1h 39mCopa Airlines
Tue 24/315:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 7/1$463
Wed 25/209:45PTY - SAL
1 stop6h 55mAvianca
Mon 9/315:45SAL - PTY
Nonstop2h 10mAvianca
Deal found 7/1$472
Wed 21/115:47PTY - CLO
Nonstop1h 50mMultiple Airlines
Sat 31/112:40CLO - PTY
1 stop4h 15mMultiple Airlines
Deal found 7/1$497
Sun 1/316:00PTY - CLO
Nonstop1h 49mCopa Airlines
Sun 29/308:46CLO - PTY
Nonstop1h 34mCopa Airlines
Deal found 7/1$563
Fri 13/211:33PTY - SAL
Nonstop2h 10mCopa Airlines
Tue 17/208:35SAL - PTY
Nonstop2h 06mCopa Airlines
Deal found 7/1$584
Wed 25/314:55PTY - CLO
2 stops7h 45mAvianca
Sat 4/416:56CLO - PTY
1 stop4h 14mAvianca
Deal found 7/1$598
Sat 7/214:55PTY - CLO
2 stops6h 20mAvianca
Sat 14/218:25CLO - PTY
2 stops6h 35mAvianca
Deal found 7/1$606

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 9 January 2026. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Melbourne

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 19/2

16:00-17:50

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Wed 25/2

15:11-16:44

Nonstop1h 33m

$404

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Tue 17/2

16:00-17:50

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Thu 5/3

05:03-06:34

Nonstop1h 31m

$404

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 13/2

16:00-17:50

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Wed 18/2

08:48-10:20

Nonstop1h 32m

$404

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 22/1

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Wed 28/1

14:04-17:10

Nonstop2h 06m

$424

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 1/4

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 5/4

04:57-08:05

Nonstop2h 08m

$424

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Tue 20/1

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Tue 27/1

08:36-11:41

Nonstop2h 05m

$424

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 12/4

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 19/4

08:33-11:41

Nonstop2h 08m

$424

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 16/3

19:25-20:39

Nonstop2h 14m

San Salvador El Salvador Intl

Mon 23/3

07:30-10:36

Nonstop2h 06m

$424

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 13/3

22:28-23:37

Nonstop2h 09m

San Salvador El Salvador Intl

Mon 16/3

13:45-16:52

Nonstop2h 07m

$424

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 11/3

22:28-23:37

Nonstop2h 09m

San Salvador El Salvador Intl

Sun 15/3

08:35-11:41

Nonstop2h 06m

$424

Flights are sorted by cheapest return flights first.

Deals found on 7/1

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Managua Augusto C Sandino, with prices starting at $605. Explore other affordable destinations below.

Managua Augusto C Sandino
Managua Augusto C Sandino
From $605
Amsterdam Schiphol
Amsterdam Schiphol
From $1,488

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Central America

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Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 9 January 2026.

  • How does Cheapflights help users find flights from Panama?

    When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

  • Why should you use Cheapflights to find cheap flight tickets from Panama?

    Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

  • Can Cheapflights find flights from Panama with no change fees?

    Yes! Cheapflights helps users easily find flights from Panama with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama?

When you search for this flight from Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama?

Cheapflights helps you find that perfect flight from Panama by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Panama with no change fees?

Yes! Cheapflights helps users easily find flights from Panama with no change fees.

Can Cheapflights notify me if prices for flights from Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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