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$224+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — SYD
25 Apr — 2 May1
1 adult
1 adult, Economy, 0 bags

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 647,157 searches. This data was last updated on 26 March 2026.

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 20/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Wed 27/5

04:55-08:05

Nonstop2h 10m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 21/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Thu 28/5

04:53-08:05

Nonstop2h 12m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 1/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 3/5

04:53-08:05

Nonstop2h 12m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Tue 19/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Fri 22/5

04:55-08:05

Nonstop2h 10m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 25/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 31/5

04:53-08:05

Nonstop2h 12m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 16/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 17/5

04:55-08:05

Nonstop2h 10m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 25/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sat 30/5

04:53-08:05

Nonstop2h 12m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Tue 19/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sat 23/5

04:55-08:05

Nonstop2h 10m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 1/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Wed 6/5

04:55-08:05

Nonstop2h 10m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 29/4

19:25-20:33

Nonstop2h 08m

San Salvador El Salvador Intl

Sat 2/5

04:53-08:05

Nonstop2h 12m

$465

Flights are sorted by cheapest return flights first.

Deals found on 26/3

Showing 1-10 of 41 resultsSorted by cheapest first
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 26 March 2026.

  • Where can you fly direct from Panama City?

    Currently, the most popular direct flight destination from Panama City is Managua.

  • How much are direct flights from Panama City?

    On average, a one-way direct flight from Panama City will cost users approximately $446. If you're looking for a direct round-trip flight from Panama City, you can expect to pay around $568.

  • What is the best time of year to fly direct from Panama City?

    If you're seeking the lowest price on a direct flight from Panama City, May is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, July offers travelers the most options.

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