This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — SYD
5 Dec — 12 Dec1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Find direct flights from Panama City within your budget
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 7,457,451 searches. This data was last updated on 5 November 2026.
Fly to
Route
Depart
Return
Price
Cheapest return flight
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Tue 15/12
09:19-12:10
Nonstop3h 51m
Mexico City Benito Juarez
Wed 31/12
00:00-01:00
Nonstop0h 00m
$293
Panama CityMexico City
PTY Panama City Tocumen Intl - MEX Mexico City Benito Juarez
PTYMEX
Panama City Tocumen Intl
Thu 31/12
21:27-00:15
Nonstop3h 48m
Mexico City Benito Juarez
Wed 31/12
00:00-01:00
Nonstop0h 00m
$300
Panama CityMedellín
PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl
PTYMDE
Panama City Tocumen Intl
Fri 27/11
06:57-08:15
Nonstop1h 18m
Medellín Jose Maria Cordova Intl
Wed 31/12
00:00-00:00
Nonstop0h 00m
$376
Panama CityMedellín
PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl
PTYMDE
Panama City Tocumen Intl
Sun 22/11
06:57-08:15
Nonstop1h 18m
Medellín Jose Maria Cordova Intl
Wed 31/12
00:00-00:00
Nonstop0h 00m
$376
Panama CityMedellín
PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl
PTYMDE
Panama City Tocumen Intl
Mon 23/11
12:54-14:15
Nonstop1h 21m
Medellín Jose Maria Cordova Intl
Wed 31/12
00:00-00:00
Nonstop0h 00m
$376
Panama CityMedellín
PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl
PTYMDE
Panama City Tocumen Intl
Sun 15/11
09:34-10:55
Nonstop1h 21m
Medellín Jose Maria Cordova Intl
Wed 31/12
00:00-00:00
Nonstop0h 00m
$376
Panama CityMedellín
PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl
PTYMDE
Panama City Tocumen Intl
Mon 30/11
06:57-08:15
Nonstop1h 18m
Medellín Jose Maria Cordova Intl
Wed 31/12
00:00-00:00
Nonstop0h 00m
$376
Panama CityMedellín
PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl
PTYMDE
Panama City Tocumen Intl
Sat 24/4
22:00-23:25
Nonstop1h 25m
Medellín Jose Maria Cordova Intl
Wed 31/12
00:00-00:00
Nonstop0h 00m
$376
Panama CityMedellín
PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl
PTYMDE
Panama City Tocumen Intl
Wed 27/1
09:32-10:55
Nonstop1h 23m
Medellín Jose Maria Cordova Intl
Wed 31/12
00:00-00:00
Nonstop0h 00m
$376
Panama CityMedellín
PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl
PTYMDE
Panama City Tocumen Intl
Thu 19/11
12:54-14:15
Nonstop1h 21m
Medellín Jose Maria Cordova Intl
Wed 31/12
00:00-00:00
Nonstop0h 00m
$376
Flights are sorted by cheapest return flights first.
Deals found on 3/11
Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Panama City
Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
PTY-SYD
PTY-MEX
PTY-MDE
PTY-SJO
PTY-CTG
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 5 November 2026.
Where can you fly direct from Panama City?
Currently, the most popular direct flight destination from Panama City is Madrid.
How much are direct flights from Panama City?
On average, a one-way direct flight from Panama City will cost users approximately $618. If you're looking for a direct round-trip flight from Panama City, you can expect to pay around $771.
What is the best time of year to fly direct from Panama City?
If you're seeking the lowest price on a direct flight from Panama City, March is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, June offers travelers the most options.
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