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$228+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MEL
1 Jan — 8 Jan1
1 adult
1 adult, Economy, 0 bags

Direct flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 2 December 2025.

Wed 31/1211:33PTY - SAL
Nonstop2h 06mCopa Airlines
Fri 2/114:04SAL - PTY
Nonstop2h 06mCopa Airlines
Deal found 1/12$316
Fri 13/212:29PTY - CLO
Nonstop1h 41mCopa Airlines
Fri 20/215:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 30/11$371
Sun 21/1219:25PTY - SAL
Nonstop2h 10mCopa Airlines
Sat 3/105:03SAL - PTY
Nonstop2h 08mCopa Airlines
Deal found 1/12$374
Thu 29/119:25PTY - SAL
Nonstop2h 13mCopa Airlines
Thu 5/205:02SAL - PTY
Nonstop2h 09mCopa Airlines
Deal found 30/11$417
Wed 17/1219:25PTY - SAL
Nonstop2h 10mCopa Airlines
Tue 23/1205:00SAL - PTY
Nonstop2h 11mCopa Airlines
Deal found 29/11$434
Sun 22/216:00PTY - CLO
Nonstop1h 50mCopa Airlines
Thu 26/215:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 29/11$450
Wed 17/1215:55PTY - CLO
Nonstop1h 42mCopa Airlines
Wed 14/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 30/11$457
Mon 29/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Thu 15/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 30/11$473
Mon 29/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Mon 12/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 30/11$489
Fri 12/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Mon 15/1212:04CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 1/12$502
Tue 16/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Fri 16/112:03CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 1/12$519
Fri 19/1215:47PTY - CLO
Nonstop1h 42mCopa Airlines
Mon 12/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 30/11$538

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 647,157 searches. This data was last updated on 2 December 2025.

Fly to

Melbourne

Route

Depart

Return

Price

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 1/1

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Mon 5/1

07:30-10:35

Nonstop2h 05m

$316

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 31/12

11:33-12:39

Nonstop2h 06m

San Salvador El Salvador Intl

Mon 5/1

07:30-10:35

Nonstop2h 05m

$316

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 31/12

19:25-20:35

Nonstop2h 10m

San Salvador El Salvador Intl

Sun 4/1

08:36-11:41

Nonstop2h 05m

$316

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 26/12

19:25-20:35

Nonstop2h 10m

San Salvador El Salvador Intl

Fri 2/1

08:36-11:41

Nonstop2h 05m

$316

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 25/12

19:25-20:35

Nonstop2h 10m

San Salvador El Salvador Intl

Sun 4/1

08:36-11:41

Nonstop2h 05m

$316

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 1/3

22:28-23:37

Nonstop2h 09m

San Salvador El Salvador Intl

Wed 4/3

13:45-16:52

Nonstop2h 07m

$316

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 19/1

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Mon 26/1

07:30-10:35

Nonstop2h 05m

$316

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 18/4

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Tue 21/4

04:57-08:05

Nonstop2h 08m

$316

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 5/1

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Tue 20/1

14:04-17:10

Nonstop2h 06m

$316

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 7/1

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Mon 12/1

05:03-08:11

Nonstop2h 08m

$316

Flights are sorted by cheapest return flights first.

Deals found on 30/11

Showing 1-10 of 37 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 2 December 2025.

  • Where can you fly direct from Panama City?

    Currently, the most popular direct flight destination from Panama City is Managua.

  • What is the best time of year to fly direct from Panama City?

    If you're seeking the lowest price on a direct flight from Panama City, May is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, October offers travelers the most options.

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