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$214+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — BNE
8 Jul — 15 Jul1
1 adult
1 adult, Economy, 0 bags

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 647,157 searches. This data was last updated on 8 June 2026.

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 19/7

05:30-06:30

Nonstop2h 00m

San Salvador El Salvador Intl

Sun 26/7

22:55-01:55

Nonstop2h 00m

$410

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Tue 7/7

19:25-20:34

Nonstop2h 09m

San Salvador El Salvador Intl

Tue 21/7

04:54-08:05

Nonstop2h 11m

$440

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 28/6

22:28-23:37

Nonstop2h 09m

San Salvador El Salvador Intl

Sun 9/8

08:30-11:41

Nonstop2h 11m

$440

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 22/7

11:33-12:42

Nonstop2h 09m

San Salvador El Salvador Intl

Wed 29/7

13:59-17:10

Nonstop2h 11m

$440

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 30/10

11:33-12:40

Nonstop2h 07m

San Salvador El Salvador Intl

Tue 3/11

04:59-08:10

Nonstop2h 11m

$440

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 2/7

11:33-12:42

Nonstop2h 09m

San Salvador El Salvador Intl

Thu 9/7

04:54-08:05

Nonstop2h 11m

$440

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 5/9

19:25-20:31

Nonstop2h 06m

San Salvador El Salvador Intl

Fri 11/9

13:59-17:10

Nonstop2h 11m

$440

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 31/8

19:25-20:31

Nonstop2h 06m

San Salvador El Salvador Intl

Thu 10/9

13:59-17:10

Nonstop2h 11m

$440

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Tue 7/7

11:33-12:42

Nonstop2h 09m

San Salvador El Salvador Intl

Mon 20/7

04:54-08:05

Nonstop2h 11m

$440

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Tue 30/6

15:55-17:36

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Thu 30/7

08:46-10:20

Nonstop1h 34m

$448

Flights are sorted by cheapest return flights first.

Deals found on 7/6

Showing 1-10 of 39 resultsSorted by cheapest first
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 8 June 2026.

  • Where can you fly direct from Panama City?

    Currently, the most popular direct flight destination from Panama City is Managua.

  • How much are direct flights from Panama City?

    On average, a one-way direct flight from Panama City will cost users approximately $582. If you're looking for a direct round-trip flight from Panama City, you can expect to pay around $766.

  • What is the best time of year to fly direct from Panama City?

    If you're seeking the lowest price on a direct flight from Panama City, March is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, April offers travelers the most options.

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