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$222+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 31/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MEL
27 Jan — 3 Feb1
1 adult
1 adult, Economy, 0 bags

Direct flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 28 December 2025.

Sun 11/111:33PTY - SAL
Nonstop2h 08mCopa Airlines
Sun 25/114:04SAL - PTY
Nonstop2h 06mCopa Airlines
Deal found 26/12$423
Thu 8/109:20PTY - CLO
Nonstop1h 40mCopa Airlines
Thu 22/112:03CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 26/12$445
Fri 9/109:20PTY - CLO
Nonstop1h 40mCopa Airlines
Fri 16/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 26/12$461
Sat 10/109:20PTY - CLO
Nonstop1h 40mCopa Airlines
Wed 14/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 27/12$476
Fri 9/109:20PTY - CLO
Nonstop1h 40mCopa Airlines
Sun 11/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 26/12$490
Fri 13/216:00PTY - CLO
Nonstop1h 50mCopa Airlines
Fri 20/215:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 26/12$533
Sun 1/312:29PTY - CLO
Nonstop1h 40mCopa Airlines
Sun 29/308:46CLO - PTY
Nonstop1h 34mCopa Airlines
Deal found 27/12$561
Fri 13/216:00PTY - CLO
Nonstop1h 50mCopa Airlines
Wed 18/205:03CLO - PTY
Nonstop1h 31mCopa Airlines
Deal found 26/12$621
Wed 11/209:25PTY - CLO
Nonstop1h 40mCopa Airlines
Tue 17/215:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 26/12$869
Mon 23/309:25PTY - CLO
Nonstop1h 39mCopa Airlines
Mon 23/315:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 27/12$1,320

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 647,157 searches. This data was last updated on 28 December 2025.

Fly to

Melbourne

Route

Depart

Return

Price

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 11/1

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Thu 15/1

05:03-08:11

Nonstop2h 08m

$423

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 15/1

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Sat 24/1

14:04-17:10

Nonstop2h 06m

$423

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 10/1

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Sat 21/2

05:02-08:11

Nonstop2h 09m

$423

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 11/1

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 25/1

14:04-17:10

Nonstop2h 06m

$423

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 10/1

19:25-20:38

Nonstop2h 13m

San Salvador El Salvador Intl

Sat 17/1

07:30-10:35

Nonstop2h 05m

$423

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 16/1

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 18/1

05:03-08:11

Nonstop2h 08m

$423

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 14/1

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 18/1

14:04-17:10

Nonstop2h 06m

$423

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 7/1

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 11/1

05:03-08:11

Nonstop2h 08m

$423

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sun 11/1

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Thu 29/1

14:04-17:10

Nonstop2h 06m

$423

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 19/2

09:25-11:05

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

Wed 25/2

08:48-10:20

Nonstop1h 32m

$445

Flights are sorted by cheapest return flights first.

Deals found on 25/12

Showing 1-10 of 27 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 28 December 2025.

  • Where can you fly direct from Panama City?

    Currently, the most popular direct flight destination from Panama City is Managua.

  • What is the best time of year to fly direct from Panama City?

    If you're seeking the lowest price on a direct flight from Panama City, May is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, July offers travelers the most options.

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