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$217+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — SYD
18 Oct — 25 Oct1
1 adult
1 adult, Economy

Direct flights from Panama City

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 18 September 2025.

Fri 7/1122:28PTY - SAL
Nonstop2h 11mCopa Airlines
Mon 10/1105:00SAL - PTY
Nonstop2h 11mCopa Airlines
Deal found 17/9$384
Mon 6/1015:40PTY - SAL
Nonstop1h 55mAvianca
Sun 19/1013:20SAL - PTY
Nonstop1h 55mAvianca
Deal found 16/9$396
Fri 24/1012:43PTY - CLO
Nonstop1h 42mCopa Airlines
Sun 9/1108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 15/9$400
Fri 5/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Sun 7/1208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 15/9$417
Sat 27/911:33PTY - SAL
Nonstop2h 03mCopa Airlines
Wed 22/1005:05SAL - PTY
Nonstop2h 06mCopa Airlines
Deal found 15/9$426
Sun 26/1012:29PTY - CLO
Nonstop1h 42mCopa Airlines
Mon 9/208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 15/9$432
Sat 1/1109:20PTY - CLO
Nonstop1h 41mCopa Airlines
Tue 18/1112:04CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 17/9$448
Tue 30/922:28PTY - SAL
Nonstop2h 07mCopa Airlines
Fri 3/1013:41SAL - PTY
Nonstop2h 10mCopa Airlines
Deal found 15/9$448
Wed 11/216:00PTY - CLO
Nonstop1h 50mCopa Airlines
Tue 17/215:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 15/9$465
Tue 30/922:28PTY - SAL
Nonstop2h 07mCopa Airlines
Sat 4/1007:30SAL - PTY
Nonstop2h 08mCopa Airlines
Deal found 17/9$469
Thu 4/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Thu 11/1212:04CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 15/9$480
Sat 1/1109:20PTY - CLO
Nonstop1h 41mCopa Airlines
Tue 4/1104:52CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 16/9$496

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 647,157 searches. This data was last updated on 18 September 2025.

Fly to

Sydney

Route

Depart

Return

Price

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 17/11

19:30-20:40

Nonstop2h 10m

San Salvador El Salvador Intl

Fri 28/11

05:00-08:11

Nonstop2h 11m

$384

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Tue 21/10

11:33-12:36

Nonstop2h 03m

San Salvador El Salvador Intl

Sat 25/10

05:05-08:11

Nonstop2h 06m

$384

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 2/10

11:33-12:36

Nonstop2h 03m

San Salvador El Salvador Intl

Sat 4/10

05:05-08:11

Nonstop2h 06m

$384

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 1/11

22:28-23:39

Nonstop2h 11m

San Salvador El Salvador Intl

Wed 5/11

08:33-11:41

Nonstop2h 08m

$384

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 31/10

22:28-23:37

Nonstop2h 09m

San Salvador El Salvador Intl

Tue 4/11

13:46-16:55

Nonstop2h 09m

$384

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 26/11

19:30-20:40

Nonstop2h 10m

San Salvador El Salvador Intl

Sun 30/11

08:33-11:41

Nonstop2h 08m

$384

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 12/11

22:28-23:39

Nonstop2h 11m

San Salvador El Salvador Intl

Fri 28/11

05:00-08:11

Nonstop2h 11m

$384

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 7/11

22:28-23:39

Nonstop2h 11m

San Salvador El Salvador Intl

Mon 10/11

05:00-08:11

Nonstop2h 11m

$384

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 2/10

19:28-20:40

Nonstop2h 12m

San Salvador El Salvador Intl

Tue 7/10

13:41-16:51

Nonstop2h 10m

$384

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 12/11

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 16/11

05:00-08:11

Nonstop2h 11m

$384

Flights are sorted by cheapest return flights first.

Deals found on 16/9

Showing 1-10 of 35 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 18 September 2025.

  • Where can you fly direct from Panama City?

    Currently, the most popular direct flight destination from Panama City is Sao Paulo Guarulhos Intl Airport.

  • What is the best time of year to fly direct from Panama City?

    If you're seeking the lowest price on a direct flight from Panama City, August is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, July offers travelers the most options.

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