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$190+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — SYD
21 Dec — 28 Dec1
1 adult
1 adult, Economy, 0 bags

Direct flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 21 November 2025.

Thu 11/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Tue 3/312:02CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 19/11$346
Fri 26/1215:50PTY - SAL
Nonstop2h 00mAvianca
Mon 5/115:45SAL - PTY
Nonstop2h 10mAvianca
Deal found 20/11$375
Fri 13/212:29PTY - CLO
Nonstop1h 41mCopa Airlines
Fri 20/208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 20/11$405
Fri 12/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Mon 15/1208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 20/11$420
Sat 20/1222:28PTY - SAL
Nonstop2h 11mCopa Airlines
Tue 30/1208:33SAL - PTY
Nonstop2h 08mCopa Airlines
Deal found 20/11$439
Mon 1/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Thu 4/1205:01CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 19/11$451
Sat 20/1222:28PTY - SAL
Nonstop2h 11mCopa Airlines
Mon 5/107:30SAL - PTY
Nonstop2h 05mCopa Airlines
Deal found 18/11$456
Fri 13/212:29PTY - CLO
Nonstop1h 41mCopa Airlines
Tue 17/208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 18/11$462
Tue 23/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Mon 29/1208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 21/11$479
Sun 22/221:55PTY - CLO
Nonstop1h 41mCopa Airlines
Thu 26/212:03CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 18/11$484
Fri 12/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Sun 14/1208:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 19/11$487
Fri 5/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Sun 7/1205:01CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 18/11$494

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 647,157 searches. This data was last updated on 21 November 2025.

Fly to

Sydney

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 16/1

15:47-17:37

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Fri 20/2

08:48-10:20

Nonstop1h 32m

$346

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 14/2

09:25-11:05

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

Fri 27/2

08:48-10:20

Nonstop1h 32m

$346

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 11/12

09:20-11:01

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 3/3

12:02-13:34

Nonstop1h 32m

$346

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 27/12

19:50-20:55

Nonstop2h 05m

San Salvador El Salvador Intl

Mon 5/1

07:30-10:30

Nonstop2h 00m

$375

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 26/12

15:50-16:50

Nonstop2h 00m

San Salvador El Salvador Intl

Mon 5/1

15:45-18:55

Nonstop2h 10m

$375

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 13/2

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Fri 20/2

08:48-10:20

Nonstop1h 32m

$405

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 10/1

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Fri 13/2

15:11-16:44

Nonstop1h 33m

$405

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 13/2

16:00-17:50

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Wed 18/2

08:48-10:20

Nonstop1h 32m

$405

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sun 15/3

09:25-11:04

Nonstop1h 39m

Cali Alfonso B. Aragon Intl

Mon 23/3

15:11-16:44

Nonstop1h 33m

$405

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 11/2

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 17/2

05:03-06:34

Nonstop1h 31m

$405

Flights are sorted by cheapest return flights first.

Deals found on 20/11

Showing 1-10 of 39 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 21 November 2025.

  • Where can you fly direct from Panama City?

    Currently, the most popular direct flight destination from Panama City is Managua.

  • What is the best time of year to fly direct from Panama City?

    If you're seeking the lowest price on a direct flight from Panama City, May is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, July offers travelers the most options.

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