$321+ Cheap flights from Des Moines

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — MEL
22 Jan — 29 Jan1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Des Moines

Discover essential information about flights departing from Des Moines, including flight schedules, destinations, airlines operating at the Des Moines airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 23 December 2025.

Good one-way deal

$1,106 or less
Price to beat on a one-way flight from Des Moines.
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Cheapest flights from Des Moines
Explore the most affordable flight options available from Des Moines. Find the lowest fares based on data from user searches, with prices last updated on 23 December 2025.

Wed 4/211:42DSM - BNE
2 stops26h 48mAmerican Airlines
Wed 11/219:40BNE - DSM
1 stop34h 54mAmerican Airlines
Deal found 21/12$1,525
Wed 4/211:30DSM - BNE
2 stops28h 00mLufthansa
Wed 11/211:40BNE - DSM
2 stops24h 54mLufthansa
Deal found 21/12$1,548
Wed 4/205:35DSM - BNE
2 stops34h 45mDelta
Wed 11/211:05BNE - DSM
2 stops26h 17mDelta
Deal found 22/12$1,569
Fri 6/215:35DSM - BNE
2 stops23h 55mUnited Airlines
Tue 10/211:40BNE - DSM
2 stops20h 48mUnited Airlines
Deal found 21/12$1,570
Thu 5/208:10DSM - BNE
2 stops31h 20mUnited Airlines
Thu 12/211:40BNE - DSM
2 stops41h 10mUnited Airlines
Deal found 22/12$1,591
Wed 4/205:35DSM - MEL
2 stops33h 25mDelta
Wed 11/210:10MEL - DSM
2 stops23h 18mDelta
Deal found 22/12$1,757
Thu 5/211:35DSM - BNE
1 stop26h 55mAmerican Airlines
Thu 12/209:40BNE - DSM
1 stop29h 58mAmerican Airlines
Deal found 22/12$1,760
Fri 6/211:26DSM - MEL
2 stops27h 34mDelta
Fri 13/210:10MEL - DSM
2 stops27h 39mDelta
Deal found 23/12$1,907
Thu 5/214:34DSM - MEL
2 stops25h 56mAmerican Airlines
Thu 12/212:00MEL - DSM
2 stops23h 55mAmerican Airlines
Deal found 22/12$1,909
Thu 5/211:30DSM - MEL
2 stops29h 30mLufthansa
Thu 12/213:00MEL - DSM
2 stops25h 41mLufthansa
Deal found 21/12$1,929
Wed 4/216:00DSM - MEL
2 stops25h 20mAmerican Airlines
Wed 11/216:05MEL - DSM
1 stop24h 18mAmerican Airlines
Deal found 20/12$1,939
Tue 6/108:00DSM - MEL
2 stops32h 30mUnited Airlines
Tue 27/111:30MEL - DSM
2 stops23h 17mUnited Airlines
Deal found 22/12$1,942

Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 23 December 2025. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Melbourne

Route

Depart

Return

Price

Des MoinesBrisbane

DSM - BNE

DSMBNE

Des Moines

Wed 4/2

11:42-06:30

2 stops26h 48m

Brisbane

Wed 11/2

19:40-14:34

1 stop34h 54m

$1,525

Des MoinesBrisbane

DSM - BNE

DSMBNE

Des Moines

Wed 4/2

05:35-08:20

2 stops34h 45m

Brisbane

Wed 11/2

11:05-21:22

2 stops26h 17m

$1,569

Des MoinesBrisbane

DSM - BNE

DSMBNE

Des Moines

Fri 6/2

11:30-07:30

2 stops28h 00m

Brisbane

Tue 10/2

11:40-23:44

2 stops28h 04m

$1,570

Des MoinesBrisbane

DSM - BNE

DSMBNE

Des Moines

Thu 5/2

08:00-07:30

2 stops31h 30m

Brisbane

Thu 12/2

11:40-22:20

2 stops26h 40m

$1,570

Des MoinesMelbourne

DSM - MEL

DSMMEL

Des Moines

Wed 4/2

12:25-08:00

2 stops26h 35m

Melbourne

Wed 11/2

10:10-21:22

2 stops28h 12m

$1,757

Des MoinesMelbourne

DSM - MEL

DSMMEL

Des Moines

Fri 6/2

11:26-08:00

2 stops27h 34m

Melbourne

Fri 13/2

10:10-20:49

2 stops27h 39m

$1,907

Des MoinesMelbourne

DSM - MEL

DSMMEL

Des Moines

Thu 5/2

15:25-09:30

1 stop25h 05m

Melbourne

Thu 12/2

12:00-18:55

2 stops23h 55m

$1,909

Des MoinesMelbourne

DSM - MEL

DSMMEL

Des Moines

Thu 5/2

11:30-10:00

2 stops29h 30m

Melbourne

Thu 12/2

13:00-21:41

2 stops25h 41m

$1,929

Des MoinesMelbourne

DSM - MEL

DSMMEL

Des Moines

Tue 6/1

15:04-09:30

2 stops25h 26m

Melbourne

Tue 27/1

11:30-23:44

2 stops29h 14m

$1,942

Des MoinesMelbourne

DSM - MEL

DSMMEL

Des Moines

Tue 3/2

13:35-09:30

2 stops26h 55m

Melbourne

Tue 10/2

11:30-22:30

2 stops28h 00m

$1,942

Flights are sorted by cheapest return flights first.

Deals found on 22/12

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Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Des Moines?

Des Moines offers frequent flights to Chicago (394 flights per day), Atlanta (112 flights per day) and Detroit (102 flights per day).

Dallas/Fort Worth
Dallas/Fort Worth
From $1,991
Los Angeles
Los Angeles
From $1,104

What is the cheapest place to fly to from Des Moines?

The cheapest city to fly to from Des Moines is Los Angeles, with prices starting at $1,104. Explore other affordable destinations below.

Los Angeles
Los Angeles
From $1,104
Dallas/Fort Worth
Dallas/Fort Worth
From $1,991

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Direct flights from Iowa

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Direct flights from Cedar Rapids

Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 23 December 2025.

  • What are the most popular destinations to fly to from Des Moines?

    For the current month, the most popular flights from Des Moines are Denver, Hyderabad, Dallas/Fort Worth Airport. Denver, Cancún, Nashville are the most popular locations from Des Moines year round.

  • What is the cheapest flight from Des Moines to anywhere?

    Users have flown out of Des Moines for as low as $1,104 to Los Angeles (prices may vary depending on the airline and departure time). On average, users have booked flights for $1,552 to fly from Des Moines.

  • How does Cheapflights help users find flights from Des Moines?

    When you search for this flight from Des Moines, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

  • Why should you use Cheapflights to find cheap flight tickets from Des Moines?

    By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Des Moines.

  • Can Cheapflights find flights from Des Moines with no change fees?

    Need flexible booking options for your flight from Des Moines ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

  • Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

    Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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How does Cheapflights help users find flights from Des Moines?

When you search for this flight from Des Moines, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

Why should you use Cheapflights to find cheap flight tickets from Des Moines?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Des Moines.

Can Cheapflights find flights from Des Moines with no change fees?

Need flexible booking options for your flight from Des Moines ? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Des Moines become cheaper?

Of course! You can now track prices for flights from Des Moines and get an alert from Cheapflights when they change. Click the bell icon next to the flight deals above and provide your email address to set up price alerts.

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