$272+ Cheap flights from Santo Domingo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
SDQ — MEX
20 Jan — 27 Jan1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Santo Domingo

Discover essential information about flights departing from Santo Domingo, including flight schedules, destinations, airlines operating at the Santo Domingo airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 21 December 2025.

Good one-way deal

$182 or less
Price to beat on a one-way flight from Santo Domingo Las Americas.
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Cheapest flights from Santo Domingo
Explore the most affordable flight options available from Santo Domingo. Find the lowest fares based on data from user searches, with prices last updated on 21 December 2025.

Wed 31/1212:40SDQ - MEX
1 stop11h 25mCopa Airlines
Wed 7/113:10MEX - SDQ
1 stop11h 07mCopa Airlines
Deal found 19/12$574
Wed 13/508:45SDQ - MEX
1 stop12h 20mCopa Airlines
Wed 20/513:10MEX - SDQ
1 stop11h 15mCopa Airlines
Deal found 20/12$584
Wed 11/214:11SDQ - MEX
1 stop9h 54mCopa Airlines
Tue 17/201:20MEX - SDQ
1 stop9h 49mCopa Airlines
Deal found 20/12$591
Tue 2/612:40SDQ - MEX
1 stop8h 25mCopa Airlines
Mon 8/602:10MEX - SDQ
1 stop9h 03mCopa Airlines
Deal found 20/12$599
Thu 1/108:50SDQ - MEX
1 stop17h 25mCopa Airlines
Thu 8/109:25MEX - SDQ
1 stop11h 30mCopa Airlines
Deal found 21/12$600
Tue 3/208:50SDQ - MEX
1 stop12h 30mCopa Airlines
Tue 10/209:25MEX - SDQ
1 stop11h 14mCopa Airlines
Deal found 20/12$609
Mon 11/512:40SDQ - MEX
1 stop14h 20mCopa Airlines
Mon 18/515:30MEX - SDQ
1 stop8h 55mCopa Airlines
Deal found 20/12$611
Tue 10/318:39SDQ - MEX
1 stop7h 36mCopa Airlines
Mon 16/301:20MEX - SDQ
1 stop12h 54mCopa Airlines
Deal found 18/12$617
Sun 31/506:04SDQ - MEX
1 stop15h 01mCopa Airlines
Sat 6/600:25MEX - SDQ
1 stop10h 48mCopa Airlines
Deal found 20/12$618
Mon 1/618:39SDQ - MEX
1 stop7h 36mCopa Airlines
Mon 8/615:30MEX - SDQ
1 stop8h 55mCopa Airlines
Deal found 20/12$624
Thu 19/314:13SDQ - MEX
1 stop12h 02mCopa Airlines
Wed 25/309:25MEX - SDQ
1 stop14h 53mCopa Airlines
Deal found 19/12$627
Fri 6/211:57SDQ - MEX
1 stop14h 18mCopa Airlines
Thu 12/201:20MEX - SDQ
1 stop14h 45mCopa Airlines
Deal found 20/12$633

Find flights from Santo Domingo within your budget

 
Find flights departing from Santo Domingo that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 21 December 2025. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Mexico City

Route

Depart

Return

Price

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Wed 28/1

08:50-19:20

1 stop12h 30m

Mexico City Benito Juarez

Tue 3/2

01:20-18:05

1 stop14h 45m

$584

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Wed 4/3

18:39-00:15

1 stop7h 36m

Mexico City Benito Juarez

Wed 11/3

15:30-02:18

1 stop8h 48m

$584

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Sat 23/5

12:10-22:05

1 stop11h 55m

Mexico City Benito Juarez

Sat 30/5

09:50-02:25

1 stop14h 35m

$584

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 19/5

12:40-19:05

1 stop8h 25m

Mexico City Benito Juarez

Mon 25/5

01:20-13:13

1 stop9h 53m

$584

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Wed 13/5

12:40-19:05

1 stop8h 25m

Mexico City Benito Juarez

Wed 20/5

15:30-02:25

1 stop8h 55m

$584

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Mon 20/4

12:08-00:15

1 stop14h 07m

Mexico City Benito Juarez

Wed 29/4

15:30-02:20

1 stop8h 50m

$584

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Wed 15/4

12:38-19:05

1 stop8h 27m

Mexico City Benito Juarez

Wed 22/4

15:30-10:54

1 stop17h 24m

$584

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Wed 25/2

08:50-19:20

1 stop12h 30m

Mexico City Benito Juarez

Wed 4/3

15:30-02:18

1 stop8h 48m

$584

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 5/5

08:45-19:05

1 stop12h 20m

Mexico City Benito Juarez

Mon 11/5

01:20-13:13

1 stop9h 53m

$584

Santo DomingoSydney

SDQ - SYD

SDQSYD

Santo Domingo Las Americas

Thu 12/3

05:00-09:15

2 stops37h 15m

Sydney Kingsford Smith

Mon 16/3

10:25-22:46

2 stops27h 21m

$2,729

Flights are sorted by cheapest return flights first.

Deals found on 19/12

Showing 1-10 of 18 results
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Best time to book a flight from Santo Domingo

Have a flexible travel schedule? Discover the best time to fly from Santo Domingo with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Santo Domingo

Get recent, data-driven insights about flights from Santo Domingo including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Santo Domingo?

Use this chart to determine the optimal time to book a return flight from Santo Domingo to Mexico City. Price data was last updated on 12 December 2025.

The best time to book flights from Santo Domingo is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo?

Currently, October is the cheapest month in which you can book a flight from Santo Domingo (average of $245). Flying from Santo Domingo in May will prove the most costly (average of $422). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

What are popular destinations to fly to from Santo Domingo?

Santo Domingo offers frequent flights to New York (304 flights per day), Miami (91 flights per day) and Madrid (71 flights per day).

Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $176
Kingston Norman Manley
Kingston Norman Manley
From $374
Atlanta Hartsfield-Jackson
Atlanta Hartsfield-Jackson
From $286

What is the cheapest place to fly to from Santo Domingo?

The cheapest city to fly to from Santo Domingo is Medellín Jose Maria Cordova Intl, with prices starting at $176. Explore other affordable destinations below.

Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $176
Atlanta Hartsfield-Jackson
Atlanta Hartsfield-Jackson
From $286
Kingston Norman Manley
Kingston Norman Manley
From $374

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Dominican Republic

Book a direct flight from one of these other cities located in Dominican Republic.
Direct flights from Santo Domingo
Direct flights from Punta Cana

Related info for your journey

Access useful and relevant information related to your journey from Santo Domingo. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 21 December 2025.

  • What are the most popular destinations to fly to from Santo Domingo?

    For the current month, the most popular flights from Santo Domingo are New York John F Kennedy Intl Airport, Newark Airport, Boston. New York John F Kennedy Intl Airport, Newark Airport, Medellín Jose Maria Cordova Intl Airport are the most popular locations from Santo Domingo year round.

  • What is the cheapest flight from Santo Domingo to anywhere?

    Users have flown out of Santo Domingo for as low as $176 to Medellín Jose Maria Cordova Intl Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for $328 to fly from Santo Domingo.

  • What is the cheapest month to fly from Santo Domingo?

    Currently, the cheapest month for flights from Santo Domingo is October. The most expensive month for flights is May. The cheapest prices are shown above but prices will vary according to departure times, airlines, class and how early you book.

  • How does Cheapflights help users find flights from Santo Domingo?

    When you search for this flight from Santo Domingo, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

  • Why should you use Cheapflights to find cheap flight tickets from Santo Domingo?

    By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Santo Domingo.

  • Can Cheapflights find flights from Santo Domingo with no change fees?

    Yes! Cheapflights helps users easily find flights from Santo Domingo with no change fees.

  • Can Cheapflights notify me if prices for flights from Santo Domingo become cheaper?

    Not ready to book yet? You can track prices for flights from Santo Domingo on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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Fly with Cheapflights

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How does Cheapflights help users find flights from Santo Domingo?

When you search for this flight from Santo Domingo, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

Why should you use Cheapflights to find cheap flight tickets from Santo Domingo?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Santo Domingo.

Can Cheapflights find flights from Santo Domingo with no change fees?

Yes! Cheapflights helps users easily find flights from Santo Domingo with no change fees.

Can Cheapflights notify me if prices for flights from Santo Domingo become cheaper?

Not ready to book yet? You can track prices for flights from Santo Domingo on Cheapflights with our Price Alerts feature and get notified when better prices are available.

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