$189+ Cheap flights from Panama City
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
What to know about flights from Panama City
Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 27 October 2025.
Good round-trip deal | $94 or less |
|---|---|
Good one-way deal | $629 or less |
Find flights from Panama City
Cheapest flights from Panama CityExplore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 27 October 2025.
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 27 October 2025.
Find flights from Panama City within your budget
Fly to
Route
Depart
Return
Price
Panama CityCali
PTY - CLO
PTYCLO
Panama City Tocumen Intl
Mon 10/11
15:47-17:29
Nonstop1h 42m
Cali Alfonso B. Aragon Intl
Fri 28/11
12:04-13:36
Nonstop1h 32m
Panama CityCali
PTY - CLO
PTYCLO
Panama City Tocumen Intl
Thu 6/11
15:47-17:29
Nonstop1h 42m
Cali Alfonso B. Aragon Intl
Sun 9/11
08:48-10:20
Nonstop1h 32m
Panama CityCali
PTY - CLO
PTYCLO
Panama City Tocumen Intl
Tue 13/1
09:20-11:00
Nonstop1h 40m
Cali Alfonso B. Aragon Intl
Sun 18/1
08:48-10:20
Nonstop1h 32m
Panama CityCali
PTY - CLO
PTYCLO
Panama City Tocumen Intl
Mon 24/11
09:20-11:01
Nonstop1h 41m
Cali Alfonso B. Aragon Intl
Sat 24/1
12:03-13:35
Nonstop1h 32m
Panama CityCali
PTY - CLO
PTYCLO
Panama City Tocumen Intl
Sat 14/2
12:29-14:10
Nonstop1h 41m
Cali Alfonso B. Aragon Intl
Sat 28/2
05:03-06:34
Nonstop1h 31m
Panama CityCali
PTY - CLO
PTYCLO
Panama City Tocumen Intl
Fri 14/11
09:20-11:01
Nonstop1h 41m
Cali Alfonso B. Aragon Intl
Sun 16/11
12:04-13:36
Nonstop1h 32m
Panama CityCali
PTY - CLO
PTYCLO
Panama City Tocumen Intl
Mon 24/11
12:29-14:11
Nonstop1h 42m
Cali Alfonso B. Aragon Intl
Fri 28/11
04:52-06:24
Nonstop1h 32m
Panama CityCali
PTY - CLO
PTYCLO
Panama City Tocumen Intl
Thu 6/11
21:55-23:37
Nonstop1h 42m
Cali Alfonso B. Aragon Intl
Mon 10/11
04:52-06:24
Nonstop1h 32m
Panama CitySan Salvador
PTY - SAL
PTYSAL
Panama City Tocumen Intl
Mon 10/11
19:50-20:55
Nonstop2h 05m
San Salvador El Salvador Intl
Fri 14/11
07:30-10:30
Nonstop2h 00m
Panama CitySan Salvador
PTY - SAL
PTYSAL
Panama City Tocumen Intl
Fri 7/11
11:33-12:41
Nonstop2h 08m
San Salvador El Salvador Intl
Mon 17/11
13:46-16:55
Nonstop2h 09m
Best time to book a flight from Panama City
Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Travel insights for flights from Panama City
Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.
What are popular destinations to fly to from Panama City?
Panama City offers frequent flights to Sao Paulo (244 flights per day), San José (139 flights per day) and Miami (103 flights per day).
What is the cheapest place to fly to from Panama City?
The cheapest city to fly to from Panama City is Bogotá El Dorado, with prices starting at $94. Explore other affordable destinations below.
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Direct flights from Panama
Book a direct flight from one of these other cities located in Panama.
Related info for your journey
Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 27 October 2025.
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