$224+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MEL
10 Jan — 17 Jan1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 11 December 2025.

Good round-trip deal

$93 or less

Good one-way deal

$472 or less
Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Find flights from Panama City

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 11 December 2025.

Wed 11/209:45PTY - SAL
1 stop6h 55mAvianca
Mon 23/322:05SAL - PTY
1 stop9h 45mAvianca
Deal found 9/12$399
Mon 29/1211:33PTY - SAL
Nonstop2h 06mCopa Airlines
Sat 3/105:03SAL - PTY
Nonstop2h 08mCopa Airlines
Deal found 9/12$427
Mon 22/1215:47PTY - CLO
Nonstop1h 42mCopa Airlines
Mon 26/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/12$450
Mon 29/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Thu 15/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/12$466
Sun 8/214:55PTY - SAL
1 stop16h 20mAvianca
Thu 26/315:45SAL - PTY
Nonstop2h 10mAvianca
Deal found 9/12$475
Tue 23/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Tue 20/108:48CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/12$481
Sun 21/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Sun 25/112:03CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/12$495
Tue 23/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Mon 29/1215:11CLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 10/12$511
Fri 13/212:29PTY - CLO
Nonstop1h 41mCopa Airlines
Wed 18/205:03CLO - PTY
Nonstop1h 31mCopa Airlines
Deal found 9/12$538
Sun 21/1215:47PTY - CLO
Nonstop1h 42mCopa Airlines
Sat 17/112:03CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/12$540
Wed 24/1209:20PTY - CLO
Nonstop1h 41mCopa Airlines
Wed 14/112:03CLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 10/12$543
Mon 29/1212:29PTY - CLO
Nonstop1h 42mCopa Airlines
Thu 8/105:03CLO - PTY
Nonstop1h 31mCopa Airlines
Deal found 9/12$555

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 11 December 2025. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Melbourne

Route

Depart

Return

Price

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Sat 3/1

19:25-20:38

Nonstop2h 13m

San Salvador El Salvador Intl

Mon 5/1

05:03-08:11

Nonstop2h 08m

$427

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 5/1

19:25-20:38

Nonstop2h 13m

San Salvador El Salvador Intl

Mon 26/1

07:30-10:35

Nonstop2h 05m

$427

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 31/12

22:28-23:39

Nonstop2h 11m

San Salvador El Salvador Intl

Sat 3/1

05:03-08:11

Nonstop2h 08m

$427

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 1/1

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Thu 8/1

05:03-08:11

Nonstop2h 08m

$427

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 1/4

19:25-20:33

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 5/4

14:02-17:10

Nonstop2h 08m

$427

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 2/1

11:33-12:41

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 11/1

08:36-11:41

Nonstop2h 05m

$427

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 31/12

22:28-23:39

Nonstop2h 11m

San Salvador El Salvador Intl

Fri 2/1

05:03-08:11

Nonstop2h 08m

$427

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 29/12

11:33-12:39

Nonstop2h 06m

San Salvador El Salvador Intl

Sat 31/1

14:04-17:10

Nonstop2h 06m

$427

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 12/3

22:28-23:37

Nonstop2h 09m

San Salvador El Salvador Intl

Sun 15/3

05:02-08:11

Nonstop2h 09m

$427

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 13/2

16:00-17:50

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Mon 16/2

12:03-13:35

Nonstop1h 32m

$450

Flights are sorted by cheapest return flights first.

Deals found on 9/12

Showing 1-10 of 60 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Panama City?

Panama City offers frequent flights to Sao Paulo (254 flights per day), San José (157 flights per day) and Miami (120 flights per day).

Managua Augusto C Sandino
Managua Augusto C Sandino
From $610
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From $472
Amsterdam Schiphol
Amsterdam Schiphol
From $1,500
Bogotá El Dorado
Bogotá El Dorado
From $93

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Bogotá El Dorado, with prices starting at $93. Explore other affordable destinations below.

Bogotá El Dorado
Bogotá El Dorado
From $93
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From $472
Managua Augusto C Sandino
Managua Augusto C Sandino
From $610
Amsterdam Schiphol
Amsterdam Schiphol
From $1,500

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 11 December 2025.

  • What are the most popular destinations to fly to from Panama City?

    For the current month, the most popular flights from Panama City are Bogotá, Cali, Barranquilla. Bogotá, Cancún, Cartagena are the most popular locations from Panama City year round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as $472 to San José (prices may vary depending on the airline and departure time). On average, users have booked flights for $863 to fly from Panama City.

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Panama City with no change fees?

    Yes, we can. To see specific flights from Panama City with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City with no change fees?

Yes, we can. To see specific flights from Panama City with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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