$224+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — SYD
25 Apr — 2 May1
1 adult
1 adult, Economy, 0 bags

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 26 March 2026. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 1/5

15:50-16:50

Nonstop2h 00m

San Salvador El Salvador Intl

Sun 3/5

10:10-14:55

1 stop3h 45m

$425

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Wed 20/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Wed 27/5

04:55-08:05

Nonstop2h 10m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 21/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Thu 28/5

04:53-08:05

Nonstop2h 12m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 1/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 3/5

04:53-08:05

Nonstop2h 12m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 25/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sun 31/5

04:53-08:05

Nonstop2h 12m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 22/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Mon 25/5

04:53-08:05

Nonstop2h 12m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Mon 25/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Sat 30/5

04:53-08:05

Nonstop2h 12m

$445

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Fri 1/5

22:28-23:36

Nonstop2h 08m

San Salvador El Salvador Intl

Wed 6/5

04:55-08:05

Nonstop2h 10m

$445

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 9/4

15:55-17:36

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 14/4

15:10-16:44

Nonstop1h 34m

$528

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 8/4

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Wed 15/4

08:46-10:20

Nonstop1h 34m

$528

Flights are sorted by cheapest return flights first.

Deals found on 26/3

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Panama City?

Panama City offers frequent flights to Sao Paulo (190 flights per day), San José (128 flights per day) and Miami (106 flights per day).

Cartagena Rafael Nunez
Cartagena Rafael Nunez
From $100
Managua Augusto C Sandino
Managua Augusto C Sandino
From $582
Montego Bay Sangster Intl
Montego Bay Sangster Intl
From $567
Bocas Del Toro
Bocas Del Toro
From $189

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Cartagena Rafael Nunez, with prices starting at $100. Explore other affordable destinations below.

Cartagena Rafael Nunez
Cartagena Rafael Nunez
From $100
Bogotá El Dorado
Bogotá El Dorado
From $186
Bocas Del Toro
Bocas Del Toro
From $189
Montego Bay Sangster Intl
Montego Bay Sangster Intl
From $567

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 26 March 2026.

  • What are the most popular destinations to fly to from Panama City?

    For the current month, the most popular flights from Panama City are Bogotá, Bocas del Toro, David. Bogotá, Cancún, Cartagena are the most popular locations from Panama City year round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as $186 to Bogotá (prices may vary depending on the airline and departure time). On average, users have booked flights for $723 to fly from Panama City.

  • What is the cheapest premium economy flight from Panama City?

    Options for some of the cheapest premium economy flights from Panama City we have found on Cheapflights are as follows:
    Fly from Panama City Tocumen Intl to Paris Charles de Gaulle Airport starting at $2,460

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Panama City with no change fees?

    Yes, we can. To see specific flights from Panama City with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

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How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City with no change fees?

Yes, we can. To see specific flights from Panama City with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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