$177+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MEL
10 Mar — 17 Mar1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 8 February 2026.

Good round-trip deal

$562 or less

Good one-way deal

$109 or less
Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Find flights from Panama City

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 8 February 2026.

Thu 5/315:50
PTY
-
SAL
Nonstop2h 00m
Avianca
Sun 8/322:25
SAL
-
PTY
1 stop15h 30m
Avianca
Deal found 7/2$305
Thu 19/216:00
PTY
-
CLO
Nonstop1h 50m
Copa Airlines
Wed 25/205:03
CLO
-
PTY
Nonstop1h 31m
Copa Airlines
Deal found 5/2$348
Wed 1/411:33
PTY
-
SAL
Nonstop2h 08m
Copa Airlines
Sun 5/408:33
SAL
-
PTY
Nonstop2h 08m
Copa Airlines
Deal found 7/2$378
Tue 7/419:25
PTY
-
SAL
Nonstop2h 08m
Copa Airlines
Tue 21/404:57
SAL
-
PTY
Nonstop2h 08m
Copa Airlines
Deal found 6/2$390
Fri 20/209:45
PTY
-
CLO
1 stop5h 00m
Avianca
Tue 17/312:40
CLO
-
PTY
1 stop4h 15m
Avianca
Deal found 6/2$400
Tue 2/603:25
PTY
-
CLO
1 stop4h 15m
Avianca
Tue 9/610:15
CLO
-
PTY
1 stop4h 00m
Avianca
Deal found 8/2$402
Fri 27/222:28
PTY
-
SAL
Nonstop2h 09m
Copa Airlines
Tue 17/305:02
SAL
-
PTY
Nonstop2h 09m
Copa Airlines
Deal found 6/2$405
Wed 15/409:25
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Fri 15/515:10
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 5/2$409
Thu 2/422:28
PTY
-
SAL
Nonstop2h 08m
Copa Airlines
Sun 5/408:33
SAL
-
PTY
Nonstop2h 08m
Copa Airlines
Deal found 6/2$452
Fri 20/212:29
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Sun 22/205:03
CLO
-
PTY
Nonstop1h 31m
Copa Airlines
Deal found 6/2$466
Fri 24/715:55
PTY
-
CLO
Nonstop1h 40m
Copa Airlines
Fri 31/708:46
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 8/2$467
Wed 3/615:55
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Wed 10/615:10
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 8/2$483

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 8 February 2026. In the last 7 days, Cheapflights users made a total of 647,157 searches

Fly to

Melbourne

Route

Depart

Return

Price

Panama CitySan Salvador

PTY - SAL

PTYSAL

Panama City Tocumen Intl

Thu 5/3

15:50-16:50

Nonstop2h 00m

San Salvador El Salvador Intl

Sun 8/3

22:25-14:55

1 stop15h 30m

$305

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 9/4

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 14/4

15:10-16:44

Nonstop1h 34m

$348

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 19/2

16:00-17:50

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Wed 25/2

08:48-10:20

Nonstop1h 32m

$348

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 5/3

12:29-14:09

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

Thu 12/3

08:48-10:20

Nonstop1h 32m

$348

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 28/2

16:00-17:50

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Fri 13/3

05:03-06:34

Nonstop1h 31m

$348

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 10/4

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sun 12/4

15:10-16:44

Nonstop1h 34m

$348

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 23/2

16:00-17:50

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Mon 2/3

12:02-13:34

Nonstop1h 32m

$348

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 13/3

16:00-17:49

Nonstop1h 49m

Cali Alfonso B. Aragon Intl

Tue 17/3

08:48-10:20

Nonstop1h 32m

$348

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 20/2

12:29-14:10

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 24/2

05:03-06:34

Nonstop1h 31m

$348

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 27/3

09:25-11:04

Nonstop1h 39m

Cali Alfonso B. Aragon Intl

Mon 30/3

05:03-06:34

Nonstop1h 31m

$348

Flights are sorted by cheapest return flights first.

Deals found on 6/2

Showing 1-10 of 60 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What are popular destinations to fly to from Panama City?

Panama City offers frequent flights to Sao Paulo (234 flights per day), San José (127 flights per day) and Miami (114 flights per day).

Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $109
Miami
Miami
From $364
Managua Augusto C Sandino
Managua Augusto C Sandino
From $578
Montego Bay Sangster Intl
Montego Bay Sangster Intl
From $562

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Medellín Jose Maria Cordova Intl, with prices starting at $109. Explore other affordable destinations below.

Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $109
Miami
Miami
From $364
Montego Bay Sangster Intl
Montego Bay Sangster Intl
From $562
Managua Augusto C Sandino
Managua Augusto C Sandino
From $578

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 8 February 2026.

  • What are the most popular destinations to fly to from Panama City?

    For the current month, the most popular flights from Panama City are Bogotá, Cancún, Bocas del Toro. Bogotá, Cancún, Cartagena are the most popular locations from Panama City year round.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as $169 to Medellín Jose Maria Cordova Intl Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for $623 to fly from Panama City.

  • What is the cheapest premium economy flight from Panama City?

    Options for some of the cheapest premium economy flights from Panama City we have found on Cheapflights are as follows:
    Fly from Panama City Tocumen Intl to Paris Charles de Gaulle Airport starting at $2,442

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

  • Can Cheapflights find flights from Panama City with no change fees?

    Yes, we can. To see specific flights from Panama City with no change fees, users can toggle flexible booking options after using the search form above to find flights.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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Fly with Cheapflights

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How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City with no change fees?

Yes, we can. To see specific flights from Panama City with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and use a valid email address to enable the Price Alerts feature. That’s it!

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